6N9F
Crystal structure of the Thermus thermophilus 70S ribosome in complex with a short substrate mimic ACCA-DPhe and bound to mRNA and P-site tRNA at 3.7A resolution
This is a non-PDB format compatible entry.
Summary for 6N9F
Entry DOI | 10.2210/pdb6n9f/pdb |
Descriptor | 23S Ribosomal RNA, 50S Ribosomal Protein L14, 50S Ribosomal Protein L15, ... (59 entities in total) |
Functional Keywords | d-amino acids, ribosome structure, peptidyl transferase center, expanded genetic code, ribosome engineering, ribosome |
Biological source | Escherichia coli More |
Total number of polymer chains | 110 |
Total formula weight | 4439064.75 |
Authors | Melnikov, S.V.,Khabibullina, N.F.,Mairhofer, E.,Vargas-Rodriguez, O.,Reynolds, N.M.,Micura, R.,Soll, D.,Polikanov, Y.S. (deposition date: 2018-12-03, release date: 2018-12-12, Last modification date: 2023-11-15) |
Primary citation | Melnikov, S.V.,Khabibullina, N.F.,Mairhofer, E.,Vargas-Rodriguez, O.,Reynolds, N.M.,Micura, R.,Soll, D.,Polikanov, Y.S. Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site. Nucleic Acids Res., 47:2089-2100, 2019 Cited by PubMed: 30520988DOI: 10.1093/nar/gky1211 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.7 Å) |
Structure validation
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