6XZ7

E. coli 50S ribosomal subunit in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet).

Summary for 6XZ7

Entry DOI	10.2210/pdb6xz7/pdb
EMDB information	10655
Descriptor	23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... (36 entities in total)
Functional Keywords	50s ribosomal subunit, dirithromycin, antibiotics, cryo-em, ribosome
Biological source	Escherichia coli (strain K12) More
Total number of polymer chains	33
Total formula weight	1404320.86
Authors	Pichkur, E.B.,Polikanov, Y.S.,Myasnikov, A.G.,Konevega, A.L. (deposition date: 2020-02-03, release date: 2020-07-22)
Primary citation	Pichkur, E.B.,Paleskava, A.,Tereshchenkov, A.G.,Kasatsky, P.,Komarova, E.S.,Shiriaev, D.I.,Bogdanov, A.A.,Dontsova, O.A.,Osterman, I.A.,Sergiev, P.V.,Polikanov, Y.S.,Myasnikov, A.G.,Konevega, A.L. Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to theE. coli70S ribosome. Rna, 26:715-723, 2020 Cited by PubMed: 32144191 DOI: 10.1261/rna.073817.119 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.1 Å)

Structure validation