6XZ7
E. coli 50S ribosomal subunit in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet).
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 23S rRNA | polymer | 2897 | 939609.3 | 1 | Escherichia coli (strain K12) | ||
| 2 | B (B) | 5S rRNA | polymer | 120 | 38790.1 | 1 | Escherichia coli (strain K12) | ||
| 3 | C (C) | 50S ribosomal protein L2 | polymer | 271 | 29663.2 | 1 | UniProt (P60422) Pfam (PF00181) Pfam (PF03947) | Escherichia coli (strain K12) | Large ribosomal subunit protein uL2 |
| 4 | D (D) | 50S ribosomal protein L3 | polymer | 209 | 22291.6 | 1 | UniProt (P60438) Pfam (PF00297) | Escherichia coli (strain K12) | Large ribosomal subunit protein uL3 |
| 5 | E (E) | 50S ribosomal protein L4 | polymer | 201 | 22121.6 | 1 | UniProt (P60723) Pfam (PF00573) | Escherichia coli (strain K12) | Large ribosomal subunit protein uL4 |
| 6 | F (F) | 50S ribosomal protein L5 | polymer | 177 | 20073.2 | 1 | UniProt (P62399) Pfam (PF00281) Pfam (PF00673) | Escherichia coli (strain K12) | Large ribosomal subunit protein uL5 |
| 7 | G (G) | 50S ribosomal protein L6 | polymer | 176 | 18801.6 | 1 | UniProt (P0AG55) Pfam (PF00347) | Escherichia coli (strain K12) | Large ribosomal subunit protein uL6 |
| 8 | H (H) | 50S ribosomal protein L10 | polymer | 135 | 14568.7 | 1 | UniProt (P0A7J3) Pfam (PF00466) | Escherichia coli (strain K12) | 50S ribosomal protein L8,Large ribosomal subunit protein uL10 |
| 9 | I (I) | 50S ribosomal protein L11 | polymer | 134 | 14020.3 | 1 | UniProt (P0A7J7) Pfam (PF03946) Pfam (PF00298) | Escherichia coli (strain K12) | |
| 10 | J (J) | 50S ribosomal protein L13 | polymer | 142 | 16050.6 | 1 | UniProt (P0AA10) Pfam (PF00572) | Escherichia coli (strain K12) | Large ribosomal subunit protein uL13 |
| 11 | K (K) | 50S ribosomal protein L14 | polymer | 123 | 13565.1 | 1 | UniProt (P0ADY3) Pfam (PF00238) | Escherichia coli (strain K12) | Large ribosomal subunit protein uL14 |
| 12 | L (L) | 50S ribosomal protein L15 | polymer | 144 | 15008.5 | 1 | UniProt (P02413) Pfam (PF00828) | Escherichia coli (strain K12) | Large ribosomal subunit protein uL15 |
| 13 | M (M) | 50S ribosomal protein L16 | polymer | 136 | 15327.3 | 1 | UniProt (P0ADY7) Pfam (PF00252) | Escherichia coli (strain K12) | Large ribosomal subunit protein uL16 |
| 14 | N (N) | 50S ribosomal protein L17 | polymer | 125 | 14193.5 | 1 | UniProt (P0AG44) Pfam (PF01196) | Escherichia coli (strain K12) | |
| 15 | O (O) | 50S ribosomal protein L18 | polymer | 117 | 12794.7 | 1 | UniProt (P0C018) Pfam (PF00861) | Escherichia coli (strain K12) | Large ribosomal subunit protein uL18 |
| 16 | P (P) | 50S ribosomal protein L19 | polymer | 114 | 13028.1 | 1 | UniProt (P0A7K6) Pfam (PF01245) | Escherichia coli (strain K12) | Large ribosomal subunit protein bL19 |
| 17 | Q (Q) | 50S ribosomal protein L20 | polymer | 117 | 13396.8 | 1 | UniProt (P0A7L3) Pfam (PF00453) | Escherichia coli (strain K12) | Large ribosomal subunit protein bL20 |
| 18 | R (R) | 50S ribosomal protein L21 | polymer | 103 | 11586.4 | 1 | UniProt (P0AG48) Pfam (PF00829) | Escherichia coli (strain K12) | Large ribosomal subunit protein bL21 |
| 19 | S (S) | 50S ribosomal protein L22 | polymer | 110 | 12253.4 | 1 | UniProt (P61175) Pfam (PF00237) | Escherichia coli (strain K12) | Large ribosomal subunit protein uL22 |
| 20 | T (T) | 50S ribosomal protein L23 | polymer | 93 | 10546.5 | 1 | UniProt (P0ADZ0) Pfam (PF00276) | Escherichia coli (strain K12) | Large ribosomal subunit protein uL23 |
| 21 | U (U) | 50S ribosomal protein L24 | polymer | 102 | 11078.9 | 1 | UniProt (P60624) Pfam (PF00467) Pfam (PF17136) | Escherichia coli (strain K12) | Large ribosomal subunit protein uL24 |
| 22 | V (V) | 50S ribosomal protein L25 | polymer | 94 | 10713.5 | 1 | UniProt (P68919) Pfam (PF01386) | Escherichia coli (strain K12) | Large ribosomal subunit protein bL25 |
| 23 | W (W) | 50S ribosomal protein L27 | polymer | 76 | 8275.5 | 1 | UniProt (P0A7L8) Pfam (PF01016) | Escherichia coli (strain K12) | Large ribosomal subunit protein bL27 |
| 24 | X (X) | 50S ribosomal protein L28 | polymer | 77 | 8896.4 | 1 | UniProt (P0A7M2) Pfam (PF00830) | Escherichia coli (strain K12) | Large ribosomal subunit protein bL28 |
| 25 | Y (Y) | 50S ribosomal protein L29 | polymer | 62 | 7155.3 | 1 | UniProt (P0A7M6) Pfam (PF00831) | Escherichia coli (strain K12) | Large ribosomal subunit protein uL29 |
| 26 | Z (Z) | 50S ribosomal protein L30 | polymer | 58 | 6423.6 | 1 | UniProt (P0AG51) Pfam (PF00327) | Escherichia coli (strain K12) | Large ribosomal subunit protein uL30 |
| 27 | AA (a) | 50S ribosomal protein L32 | polymer | 56 | 6332.2 | 1 | UniProt (P0A7N4) Pfam (PF01783) | Escherichia coli (strain K12) | Large ribosomal subunit protein bL32 |
| 28 | BA (b) | 50S ribosomal protein L33 | polymer | 51 | 5928.0 | 1 | UniProt (P0A7N9) Pfam (PF00471) | Escherichia coli (strain K12) | Large ribosomal subunit protein bL33 |
| 29 | CA (c) | 50S ribosomal protein L34 | polymer | 46 | 5397.5 | 1 | UniProt (P0A7P5) Pfam (PF00468) | Escherichia coli (strain K12) | Large ribosomal subunit protein bL34 |
| 30 | DA (d) | 50S ribosomal protein L35 | polymer | 64 | 7181.8 | 1 | UniProt (P0A7Q1) Pfam (PF01632) | Escherichia coli (strain K12) | Large ribosomal subunit protein bL35,Ribosomal protein A |
| 31 | EA (e) | 50S ribosomal protein L36 | polymer | 38 | 4377.4 | 1 | UniProt (P0A7Q6) Pfam (PF00444) | Escherichia coli (strain K12) | Large ribosomal subunit protein bL36-A,Ribosomal protein B |
| 32 | FA (f) | Deacylated tRNAi(Met) | polymer | 76 | 24541.7 | 1 | GenBank (745369752) | Escherichia coli (strain K12) | |
| 33 | GA (g) | fMet-Phe-tRNA(Phe) | polymer | 76 | 25167.5 | 1 | Saccharomyces cerevisiae (baker's yeast) | ||
| 34 | AB, AC, AD, AE, AF... (A, B, U) | MAGNESIUM ION | non-polymer | 24.3 | 178 | Chemie (MG) | |||
| 35 | ZG (A) | Dirithromycin | non-polymer | 835.1 | 1 | Chemie (DI0) | |||
| 36 | EH, FH, GH, HH, IH... (A, B, C, D, E...) | water | water | 18.0 | 528 | Chemie (HOH) |
Sequence modifications
H: 2 - 136 (UniProt: P0A7J3)
| PDB | External Database | Details |
|---|---|---|
| Val 85 | Ser 85 | conflict |
| Thr 86 | Met 86 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 33 |
| Total formula weight | 1399159.5 | |
| Non-Polymers* | Number of molecules | 179 |
| Total formula weight | 5161.4 | |
| All* | Total formula weight | 1404320.9 |
