6ND6
Crystal structure of the Thermus thermophilus 70S ribosome in complex with erythromycin and bound to mRNA and A-, P-, and E-site tRNAs at 2.85A resolution
This is a non-PDB format compatible entry.
Summary for 6ND6
Entry DOI | 10.2210/pdb6nd6/pdb |
Descriptor | 23S Ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (60 entities in total) |
Functional Keywords | chloramphenicol, erythromycin, competition, antibiotic, 70s ribosome, inhibition of translation, peptidyl transferase center, nascent peptide exit tunnel, ribosome, ribosome-antibiotic complex, ribosome/antibiotic |
Biological source | Escherichia coli More |
Total number of polymer chains | 112 |
Total formula weight | 4572351.56 |
Authors | Svetlov, M.S.,Plessa, E.,Chen, C.-W.,Bougas, A.,Krokidis, M.G.,Dinos, G.P.,Polikanov, Y.S. (deposition date: 2018-12-13, release date: 2019-02-20, Last modification date: 2023-11-15) |
Primary citation | Svetlov, M.S.,Plessa, E.,Chen, C.W.,Bougas, A.,Krokidis, M.G.,Dinos, G.P.,Polikanov, Y.S. High-resolution crystal structures of ribosome-bound chloramphenicol and erythromycin provide the ultimate basis for their competition. RNA, 25:600-606, 2019 Cited by PubMed: 30733327DOI: 10.1261/rna.069260.118 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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