3K7J

Crystal structure of the D100E mutant of the Indian Hedgehog N-terminal signalling domain

Summary for 3K7J

• Entry DOI: 10.2210/pdb3k7j/pdb
• Related: 3k7g 3k7h 3k7i
• Descriptor: Indian hedgehog protein, ZINC ION, SULFATE ION, ... (5 entities in total)
• Functional Keywords: alpha+beta sandwich, autocatalytic cleavage, cell membrane, developmental protein, disease mutation, glycoprotein, hydrolase, lipoprotein, membrane, palmitate, protease, secreted, signaling protein
• Biological source: Homo sapiens (human)
• Cellular location: Indian hedgehog protein N-product: Cell membrane; Lipid-anchor; Extracellular side (By similarity). Indian hedgehog protein C-product: Secreted, extracellular space (By similarity): Q14623
• Total number of polymer chains: 1
• Total formula weight: 21735.39

Authors

He, Y.-X.,Kang, Y.,Zhang, W.J.,Yu, J.,Ma, G.,Zhou, C.-Z. (deposition date: 2009-10-13, release date: 2011-01-26, Last modification date: 2023-11-01)

• Primary citation: He, Y.-X.,Kang, Y.,Zhang, W.J.,Yu, J.,Ma, G.,Zhou, C.-Z.; Crystal structure of the D100E mutant of the Indian Hedgehog N-terminal signalling domain; To be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)