6XZA

E. coli 70S ribosome in complex with dirithromycin, and deacylated tRNA(iMet) (focused classification).

This is a non-PDB format compatible entry.

Summary for 6XZA

• Entry DOI: 10.2210/pdb6xza/pdb
• EMDB information: 10656
• Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... (54 entities in total)
• Functional Keywords: 70s ribosome, dirithromycin, antibiotics, cryo-em, ribosome
• Biological source: Escherichia coli K-12; More
• Total number of polymer chains: 53
• Total formula weight: 2139744.22

Authors

Pichkur, E.B.,Polikanov, Y.S.,Myasnikov, A.G.,Konevega, A.L. (deposition date: 2020-02-03, release date: 2020-11-04, Last modification date: 2024-04-24)

• Primary citation: Pichkur, E.B.,Paleskava, A.,Tereshchenkov, A.G.,Kasatsky, P.,Komarova, E.S.,Shiriaev, D.I.,Bogdanov, A.A.,Dontsova, O.A.,Osterman, I.A.,Sergiev, P.V.,Polikanov, Y.S.,Myasnikov, A.G.,Konevega, A.L.; Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to the E. coli 70S ribosome.; Rna, 26:715-723, 2020; PubMed: 32144191; DOI: 10.1261/rna.073817.119

Experimental method

ELECTRON MICROSCOPY (2.66 Å)