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PDB: 97 results

3RZF
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Crystal Structure of Inhibitor of kappaB kinase beta (I4122)
Descriptor: (4-{[4-(4-chlorophenyl)pyrimidin-2-yl]amino}phenyl)[4-(2-hydroxyethyl)piperazin-1-yl]methanone, MGC80376 protein
Authors:Xu, G, Lo, Y.C, Li, Q, Napolitano, G, Wu, X, Jiang, X, Dreano, M, Karin, M, Wu, H.
Deposit date:2011-05-11
Release date:2011-05-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystal structure of inhibitor of KappaB kinase Beta.
Nature, 472, 2011
7NL6
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Crystal Structure of DC-SIGN in complex with a triazole-based glycomimetic ligand
Descriptor: CALCIUM ION, DC-SIGN, CRD domain, ...
Authors:Jakob, R.P, Cramer, J, Lakkaichi, A, Aliu, B, Cattaneo, I, Klein, S, Jiang, X, Rabbani, S, Schwardt, O, Ernst, B, Maier, T.
Deposit date:2021-02-22
Release date:2021-10-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Sweet Drugs for Bad Bugs: A Glycomimetic Strategy against the DC-SIGN-Mediated Dissemination of SARS-CoV-2.
J.Am.Chem.Soc., 143, 2021
7NL7
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Crystal Structure of DC-SIGN in complex with a triazole-based glycomimetic ligand
Descriptor: 3-Aminopropyl 2-deoxy-2-(4-phenyl-1,2,3-triazol-1-yl)-alpha-D-mannopyranoside, CALCIUM ION, DC-SIGN, ...
Authors:Jakob, R.P, Cramer, J, Lakkaichi, A, Aliu, B, Cattaneo, I, Klein, S, Jiang, X, Rabbani, S, Schwardt, O, Ernst, B, Maier, T.
Deposit date:2021-02-22
Release date:2021-10-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Sweet Drugs for Bad Bugs: A Glycomimetic Strategy against the DC-SIGN-Mediated Dissemination of SARS-CoV-2.
J.Am.Chem.Soc., 143, 2021
4ESR
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Molecular and Structural Characterization of the SH3 Domain of AHI-1 in Regulation of Cellular Resistance of BCR-ABL+ Chronic Myeloid Leukemia Cells to Tyrosine Kinase Inhibitors
Descriptor: DI(HYDROXYETHYL)ETHER, Jouberin
Authors:Van Petegem, X.F, Liu, P.X, Lobo, P, Jiang, X.
Deposit date:2012-04-23
Release date:2012-06-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Molecular and structural characterization of the SH3 domain of AHI-1 in regulation of cellular resistance of BCR-ABL(+) chronic myeloid leukemia cells to tyrosine kinase inhibitors.
Proteomics, 12, 2012
6UT9
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Crystal structure of the carbohydrate-binding domain VP8* of human P[4] rotavirus strain BM5265
Descriptor: Outer capsid protein VP4
Authors:Xu, S, Stuckert, M, Burnside, R, McGinnis, K, Jiang, X, Kennedy, M.A.
Deposit date:2019-10-29
Release date:2020-11-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Structural basis of P[II] rotavirus evolution and host ranges under selection of histo-blood group antigens.
Proc.Natl.Acad.Sci.USA, 118, 2021
6VKX
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Crystal structure of the carbohydrate-binding domain VP8* of human P[8] rotavirus strain BM13851
Descriptor: DI(HYDROXYETHYL)ETHER, Outer capsid protein VP4, TETRAETHYLENE GLYCOL
Authors:Xu, S, McGinnis, K.R, Jiang, X, Kennedy, M.A.
Deposit date:2020-01-22
Release date:2021-01-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Structural basis of P[II] rotavirus evolution and host ranges under selection of histo-blood group antigens.
Proc.Natl.Acad.Sci.USA, 118, 2021
5K0X
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Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC2541
Descriptor: (7S)-7-amino-N-[(4-fluorophenyl)methyl]-8-oxo-2,9,16,18,21-pentaazabicyclo[15.3.1]henicosa-1(21),17,19-triene-20-carboxamide, CHLORIDE ION, Tyrosine-protein kinase Mer
Authors:McIver, A.L, Zhang, W, Liu, Q, Jiang, X, Stashko, M.A, Nichols, J, Miley, M.J, Norris-Drouin, J, Machius, M, DeRyckere, D, Wood, E, Graham, D.K, Earp, H.S, Kireev, D, Frye, S.V, Wang, X.
Deposit date:2016-05-17
Release date:2017-02-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.231 Å)
Cite:Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors.
ChemMedChem, 12, 2017
6JKF
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Crystal structure of Serratia marcescens Chitinase B complexed with compound 2-8-s2
Descriptor: 6-azanyl-11-methyl-2-oxidanylidene-7-[[(2R)-oxolan-2-yl]methyl]-N-(pyridin-3-ylmethyl)-1,9-diaza-7-azoniatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,6,9,11,13-hexaene-5-carboxamide, Chitinase
Authors:Yang, Q, Jiang, X.
Deposit date:2019-02-28
Release date:2020-02-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:A Series of Compounds Bearing a Dipyrido-Pyrimidine Scaffold Acting as Novel Human and Insect Pest Chitinase Inhibitors.
J.Med.Chem., 63, 2020
5ERG
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Crystal structure of the two-subunit tRNA m1A58 methyltransferase TRM6-TRM61 in complex with SAM
Descriptor: S-ADENOSYLMETHIONINE, tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61, tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6
Authors:Zhu, Y, Wang, M, Wang, C, Fan, X, Jiang, X, Teng, M, Li, X.
Deposit date:2015-11-14
Release date:2016-09-14
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.202 Å)
Cite:Crystal structure of the two-subunit tRNA m(1)A58 methyltransferase TRM6-TRM61 from Saccharomyces cerevisiae.
Sci Rep, 6, 2016
5EQJ
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Crystal structure of the two-subunit tRNA m1A58 methyltransferase from Saccharomyces cerevisiae
Descriptor: tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61, tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6
Authors:Zhu, Y, Wang, M, Wang, C, Fan, X, Jiang, X, Teng, M, Li, X.
Deposit date:2015-11-13
Release date:2016-09-14
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the two-subunit tRNA m(1)A58 methyltransferase TRM6-TRM61 from Saccharomyces cerevisiae.
Sci Rep, 6, 2016
6FXN
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Crystal structure of human BAFF in complex with Fab fragment of anti-BAFF antibody belimumab
Descriptor: Tumor necrosis factor ligand superfamily member 13B, belimumab heavy chain, belimumab light chain
Authors:Lammens, A, Maskos, K, Willen, L, Jiang, X, Schneider, P.
Deposit date:2018-03-09
Release date:2018-04-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors.
Nat Commun, 9, 2018
6NIW
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Crystal structure of P[6] rotavirus
Descriptor: DI(HYDROXYETHYL)ETHER, Protease-sensitive outer capsid protein
Authors:Xu, S, Liu, Y, Lakamp, L, Ahmed, L, Jiang, X, Kennedy, M.A.
Deposit date:2019-01-01
Release date:2020-01-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Molecular basis of P[II] major human rotavirus VP8* domain recognition of histo-blood group antigens.
Plos Pathog., 16, 2020
6OAI
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BU of 6oai by Molmil
Crystal structure of P[6] rotavirus vp8* complexed with LNFPI
Descriptor: Protease-sensitive outer capsid protein, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Xu, S, Liu, Y, Jiang, X, Kennedy, M.A.
Deposit date:2019-03-16
Release date:2020-03-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis of P[II] major human rotavirus VP8* domain recognition of histo-blood group antigens.
Plos Pathog., 16, 2020
1Z1D
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BU of 1z1d by Molmil
Structural Model for the interaction between RPA32 C-terminal domain and SV40 T antigen origin binding domain.
Descriptor: Large T antigen, Replication protein A 32 kDa subunit
Authors:Arunkumar, A.I, Klimovich, V, Jiang, X, Ott, R.D, Mizoue, L, Fanning, E, Chazin, W.J.
Deposit date:2005-03-03
Release date:2005-05-17
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Insights into hRPA32 C-terminal domain--mediated assembly of the simian virus 40 replisome.
Nat.Struct.Mol.Biol., 12, 2005
5DPM
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BU of 5dpm by Molmil
Crystal structure of UbiG mutant in complex with SAH
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, Ubiquinone biosynthesis O-methyltransferase
Authors:Zhu, Y, Jiang, X, Li, X, Teng, M.
Deposit date:2015-09-13
Release date:2016-09-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of UbiG mutant in complex with SAH at 2.1 angstroms resolution
To Be Published
7SPT
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BU of 7spt by Molmil
Crystal structure of exofacial state human glucose transporter GLUT3
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Solute carrier family 2, facilitated glucose transporter member 3, ...
Authors:Wang, N, Jiang, X, Yan, N.
Deposit date:2021-11-03
Release date:2022-05-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular basis for inhibiting human glucose transporters by exofacial inhibitors.
Nat Commun, 13, 2022
7SPS
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BU of 7sps by Molmil
Crystal structure of human glucose transporter GLUT3 bound with exofacial inhibitor SA47
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Solute carrier family 2, facilitated glucose transporter member 3, ...
Authors:Wang, N, Jiang, X, Yan, N.
Deposit date:2021-11-03
Release date:2022-05-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular basis for inhibiting human glucose transporters by exofacial inhibitors.
Nat Commun, 13, 2022
5DAF
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Crystal Structure of Human KEAP1 BTB Domain in Complex with Small Molecule TX64063
Descriptor: (5aS,6S,9aS)-7-hydroxy-2,6,9a-trimethyl-3-(pyridin-3-yl)-4,5,5a,6,9,9a-hexahydro-2H-benzo[g]indazole-8-carbonitrile, Kelch-like ECH-associated protein 1
Authors:Huerta, C, Jiang, X, Trevino, I, Bender, C.F, Swinger, K.K, Stoll, V.S, Ferguson, D.A, Thomas, P.J, Probst, B, Dulubova, I, Visnick, M, Wigley, W.C.
Deposit date:2015-08-19
Release date:2016-08-10
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding.
Biochim.Biophys.Acta, 1860, 2016
5DAD
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BU of 5dad by Molmil
Crystal Structure of Human KEAP1 BTB Domain in Complex with Small Molecule TX64014
Descriptor: (6aS,7S,10aS)-8-hydroxy-4-methoxy-2,7,10a-trimethyl-5,6,6a,7,10,10a-hexahydrobenzo[h]quinazoline-9-carbonitrile, Kelch-like ECH-associated protein 1
Authors:Huerta, C, Jiang, X, Trevino, I, Bender, C.F, Swinger, K.K, Stoll, V.S, Ferguson, D.A, Thomas, P.J, Probst, B, Dulubova, I, Visnick, M, Wigley, W.C.
Deposit date:2015-08-19
Release date:2016-08-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding.
Biochim.Biophys.Acta, 1860, 2016
4RDJ
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BU of 4rdj by Molmil
Crystal structure of Norovirus Boxer P domain
Descriptor: Capsid
Authors:Hao, N, Chen, Y, Xia, M, Liu, W, Tan, M, Jiang, X, Li, X.
Deposit date:2014-09-19
Release date:2015-01-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structures of GI.8 Boxer virus P dimers in complex with HBGAs, a novel evolutionary path selected by the Lewis epitope.
Protein Cell, 6, 2015
2LIT
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BU of 2lit by Molmil
NMR Solution Structure of Yeast Iso-1-cytochrome c Mutant P71H in reduced states
Descriptor: Cytochrome c iso-1, HEME C
Authors:Lan, W, Wang, Z, Yang, Z, Zhu, J, Ying, T, Jiang, X, Zhang, X, Wu, H, Liu, M, Tan, X, Cao, C, Huang, Z.X.
Deposit date:2011-08-31
Release date:2011-12-07
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Conformational toggling of yeast iso-1-cytochrome C in the oxidized and reduced States.
Plos One, 6, 2011
2LIR
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BU of 2lir by Molmil
NMR Solution Structure of Yeast Iso-1-cytochrome c Mutant P71H in oxidized states
Descriptor: Cytochrome c iso-1, HEME C
Authors:Lan, W, Wang, Z, Yang, Z, Zhu, J, Ying, T, Jiang, X, Zhang, X, Wu, H, Liu, M, Tan, X, Cao, C, Huang, Z.X.
Deposit date:2011-08-31
Release date:2011-12-07
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Conformational toggling of yeast iso-1-cytochrome C in the oxidized and reduced States.
Plos One, 6, 2011
4ZCH
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BU of 4zch by Molmil
Single-chain human APRIL-BAFF-BAFF Heterotrimer
Descriptor: TRIS-HYDROXYMETHYL-METHYL-AMMONIUM, Tumor necrosis factor ligand superfamily member 13,Tumor necrosis factor ligand superfamily member 13B,Tumor necrosis factor ligand superfamily member 13B
Authors:Lammens, A, Jiang, X, Maskos, K, Schneider, P.
Deposit date:2015-04-16
Release date:2015-05-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Stoichiometry of Heteromeric BAFF and APRIL Cytokines Dictates Their Receptor Binding and Signaling Properties.
J.Biol.Chem., 290, 2015
5WZZ
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BU of 5wzz by Molmil
The SIAH E3 ubiquitin ligases promote Wnt/ beta-catenin signaling through mediating Wnt-induced Axin degradation
Descriptor: Axin-1, E3 ubiquitin-protein ligase SIAH1, ZINC ION
Authors:Ji, L, Jiang, B, Jiang, X, Charlat, O, Chen, A, Mickanin, C, Bauer, A, Xu, W, Yan, X.-X, Cong, F.
Deposit date:2017-01-19
Release date:2017-08-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.103 Å)
Cite:The SIAH E3 ubiquitin ligases promote Wnt/ beta-catenin signaling through mediating Wnt-induced Axin degradation
Genes Dev., 31, 2017
2OBR
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Crystal Structures of P Domain of Norovirus VA387
Descriptor: Capsid protein
Authors:Cao, S, Lou, Z, Jiang, X, Zhang, X.C, Li, X, Rao, Z.
Deposit date:2006-12-20
Release date:2007-04-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the recognition of blood group trisaccharides by norovirus.
J.Virol., 81, 2007

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數據於2024-06-26公開中

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