4ZCH

Single-chain human APRIL-BAFF-BAFF Heterotrimer

Summary for 4ZCH

Entry DOI	10.2210/pdb4zch/pdb
Descriptor	Tumor necrosis factor ligand superfamily member 13,Tumor necrosis factor ligand superfamily member 13B,Tumor necrosis factor ligand superfamily member 13B, TRIS-HYDROXYMETHYL-METHYL-AMMONIUM (3 entities in total)
Functional Keywords	b-cell activating factor, a proliferation-inducing ligand, tnf superfamily; cytokine, proteros biostructures gmbh, cytokine
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	97585.04
Authors	Lammens, A.,Jiang, X.,Maskos, K.,Schneider, P. (deposition date: 2015-04-16, release date: 2015-05-13, Last modification date: 2024-01-10)
Primary citation	Schuepbach-Mallepell, S.,Das, D.,Willen, L.,Vigolo, M.,Tardivel, A.,Lebon, L.,Kowalczyk-Quintas, C.,Nys, J.,Smulski, C.,Zheng, T.S.,Maskos, K.,Lammens, A.,Jiang, X.,Hess, H.,Tan, S.L.,Schneider, P. Stoichiometry of Heteromeric BAFF and APRIL Cytokines Dictates Their Receptor Binding and Signaling Properties. J.Biol.Chem., 290:16330-16342, 2015 Cited by PubMed: 25953898 DOI: 10.1074/jbc.M115.661405 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.43 Å)

Structure validation