7NL7
Crystal Structure of DC-SIGN in complex with a triazole-based glycomimetic ligand
Summary for 7NL7
Entry DOI | 10.2210/pdb7nl7/pdb |
Descriptor | DC-SIGN, CRD domain, CALCIUM ION, 3-Aminopropyl 2-deoxy-2-(4-phenyl-1,2,3-triazol-1-yl)-alpha-D-mannopyranoside, ... (4 entities in total) |
Functional Keywords | lectin, sugar binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 18644.68 |
Authors | Jakob, R.P.,Cramer, J.,Lakkaichi, A.,Aliu, B.,Cattaneo, I.,Klein, S.,Jiang, X.,Rabbani, S.,Schwardt, O.,Ernst, B.,Maier, T. (deposition date: 2021-02-22, release date: 2021-10-27, Last modification date: 2024-01-31) |
Primary citation | Cramer, J.,Lakkaichi, A.,Aliu, B.,Jakob, R.P.,Klein, S.,Cattaneo, I.,Jiang, X.,Rabbani, S.,Schwardt, O.,Zimmer, G.,Ciancaglini, M.,Abreu Mota, T.,Maier, T.,Ernst, B. Sweet Drugs for Bad Bugs: A Glycomimetic Strategy against the DC-SIGN-Mediated Dissemination of SARS-CoV-2. J.Am.Chem.Soc., 143:17465-17478, 2021 Cited by PubMed: 34652144DOI: 10.1021/jacs.1c06778 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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