7NL7
Crystal Structure of DC-SIGN in complex with a triazole-based glycomimetic ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DC-SIGN, CRD domain | polymer | 159 | 18160.1 | 1 | UniProt (Q9NNX6) Pfam (PF00059) | Homo sapiens (Human) | C-type lectin domain family 4 member L,Dendritic cell-specific ICAM-3-grabbing non-integrin 1,DC-SIGN,DC-SIGN1,CD209 antigen |
| 2 | B, C, D (A) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 3 | E (A) | 3-Aminopropyl 2-deoxy-2-(4-phenyl-1,2,3-triazol-1-yl)-alpha-D-mannopyranoside | non-polymer | 364.4 | 1 | Chemie (UH5) | |||
| 4 | F (A) | water | water | 18.0 | 80 | Chemie (HOH) |
Sequence modifications
A: 250 - 404 (UniProt: Q9NNX6)
| PDB | External Database | Details |
|---|---|---|
| Gly 246 | - | expression tag |
| Ser 247 | - | expression tag |
| His 248 | - | expression tag |
| Met 249 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18160.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 484.6 | |
| All* | Total formula weight | 18644.7 |
