6JKF

Crystal structure of Serratia marcescens Chitinase B complexed with compound 2-8-s2

Summary for 6JKF

Entry DOI	10.2210/pdb6jkf/pdb
Descriptor	Chitinase, 6-azanyl-11-methyl-2-oxidanylidene-7-[[(2R)-oxolan-2-yl]methyl]-N-(pyridin-3-ylmethyl)-1,9-diaza-7-azoniatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,6,9,11,13-hexaene-5-carboxamide (3 entities in total)
Functional Keywords	chitinase, complex, serratia marcescens, hydrolase
Biological source	Serratia marcescens
Total number of polymer chains	2
Total formula weight	111935.97
Authors	Yang, Q.,Jiang, X. (deposition date: 2019-02-28, release date: 2020-02-19, Last modification date: 2023-11-22)
Primary citation	Jiang, X.,Kumar, A.,Motomura, Y.,Liu, T.,Zhou, Y.,Moro, K.,Zhang, K.Y.J.,Yang, Q. A Series of Compounds Bearing a Dipyrido-Pyrimidine Scaffold Acting as Novel Human and Insect Pest Chitinase Inhibitors. J.Med.Chem., 63:987-1001, 2020 Cited by PubMed: 31928006 DOI: 10.1021/acs.jmedchem.9b01154 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.99 Å)

Structure validation