Crystal structure of the two-subunit tRNA m1A58 methyltransferase TRM6-TRM61 in complex with SAM

Summary for 5ERG

DescriptortRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6, tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61, S-ADENOSYLMETHIONINE, ... (4 entities in total)
Functional Keywordstrna, complex, sam, methylation, transferase
Biological sourceSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Cellular locationNucleus  P41814 P46959
Total number of polymer chains2
Total molecular weight100106.61
Zhu, Y.,Wang, M.,Wang, C.,Fan, X.,Jiang, X.,Teng, M.,Li, X. (deposition date: 2015-11-14, release date: 2016-09-14)
Primary citation
Wang, M.,Zhu, Y.,Wang, C.,Fan, X.,Jiang, X.,Ebrahimi, M.,Qiao, Z.,Niu, L.,Teng, M.,Li, X.
Crystal structure of the two-subunit tRNA m(1)A58 methyltransferase TRM6-TRM61 from Saccharomyces cerevisiae.
Sci Rep, 6:32562-32562, 2016
PubMed: 27582183 (PDB entries with the same primary citation)
DOI: 10.1038/srep32562
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.212100.9%2.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report