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PDB: 42908 件

2IYP
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product rup
分子名称: 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING, ADENOSINE-2'-5'-DIPHOSPHATE, ...
著者Sundaramoorthy, R, Iulek, J, Hunter, W.N.
登録日2006-07-21
公開日2007-01-23
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Crystal Structures of a Bacterial 6-Phosphogluconate Dehydrogenase Reveal Aspects of Specificity, Mechanism and Mode of Inhibition by Analogues of High-Energy Reaction Intermediates.
FEBS J., 274, 2007
2VQA
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Protein-folding location can regulate Mn versus Cu- or Zn-binding. Crystal Structure of MncA.
分子名称: ACETATE ION, MANGANESE (II) ION, SLL1358 PROTEIN
著者Tottey, S, Waldron, K.J, Firbank, S.J, Reale, B, Bessant, C, Sato, K, Gray, J, Banfield, M.J, Dennison, C, Robinson, N.J.
登録日2008-03-12
公開日2008-10-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Protein-Folding Location Can Regulate Manganese-Binding Versus Copper- or Zinc-Binding.
Nature, 455, 2008
3OU1
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MDR769 HIV-1 protease complexed with RH/IN hepta-peptide
分子名称: MDR HIV-1 protease, RH/IN substrate peptide
著者Liu, Z, Wang, Y, Brunzelle, J, Kovari, I.A, Kovari, L.C.
登録日2010-09-14
公開日2011-03-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Nine Crystal Structures Determine the Substrate Envelope of the MDR HIV-1 Protease.
Protein J., 30, 2011
2W2N
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WT PCSK9-deltaC bound to EGF-A H306Y mutant of LDLR
分子名称: CALCIUM ION, LOW-DENSITY LIPOPROTEIN RECEPTOR, PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9
著者Bottomley, M.J, Cirillo, A, Orsatti, L, Ruggeri, L, Fisher, T.S, Santoro, J.C, Cummings, R.T, Cubbon, R.M, Lo Surdo, P, Calzetta, A, Noto, A, Baysarowich, J, Mattu, M, Talamo, F, De Francesco, R, Sparrow, C.P, Sitlani, A, Carfi, A.
登録日2008-11-03
公開日2008-11-18
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Biochemical Characterization of the Wild Type Pcsk9/Egf-Ab Complex and Natural Fh Mutants.
J.Biol.Chem., 284, 2009
3GV6
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Crystal Structure of human chromobox homolog 6 (CBX6) with H3K9 peptide
分子名称: Chromobox protein homolog 6, Histone H3K9me3 peptide
著者Dong, A, Amaya, M.F, Li, Z, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2009-03-30
公開日2009-04-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Recognition and specificity determinants of the human cbx chromodomains.
J.Biol.Chem., 286, 2011
2J6B
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crystal structure of AFV3-109, a highly conserved protein from crenarchaeal viruses
分子名称: AFV3-109
著者Keller, J, Leulliot, N, Cambillau, C, Campanacci, V, Porciero, S, Prangishvili, D, Cortez, D, Quevillon-Cheruel, S, Van Tilbeurgh, H.
登録日2006-09-27
公開日2007-02-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal Structure of Afv3-109, a Highly Conserved Protein from Crenarchaeal Viruses.
Virol J., 4, 2007
2VRW
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Critical structural role for the PH and C1 domains of the Vav1 exchange factor
分子名称: PROTO-ONCOGENE VAV, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1, ZINC ION
著者Rapley, J, Tybulewicz, V, Rittinger, K.
登録日2008-04-16
公開日2008-06-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crucial Structural Role for the Ph and C1 Domains of the Vav1 Exchange Factor.
Embo Rep., 9, 2008
3R0F
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Human enterovirus 71 3C protease mutant H133G in complex with rupintrivir
分子名称: 1,2-ETHANEDIOL, 3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
著者Wang, J, Fan, T, Yao, X, Wu, Z, Guo, L, Lei, X, Wang, J, Wang, M, Jin, Q, Cui, S.
登録日2011-03-08
公開日2011-08-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.3083 Å)
主引用文献Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues.
J.Virol., 85, 2011
9EZ8
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Cryo-EM structure of the icosahedral lumazine synthase from Vicia faba.
分子名称: 6,7-dimethyl-8-ribityllumazine synthase
著者Chee, M, Trapani, S, Hoh, F, Lai Kee Him, J, Yvon, M, Blanc, S, Bron, P.
登録日2024-04-11
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Cryo-EM structure of the icosahedral lumazine synthase from Vicia faba.
To Be Published
2NDJ
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Structural Basis for KCNE3 and Estrogen Modulation of the KCNQ1 Channel
分子名称: Potassium voltage-gated channel subfamily E member 3
著者Sanders, C.R, Van Horn, W.D, Kroncke, B.M, Sisco, N.J, Meiler, J, Vanoye, C.G, Song, Y, Nannemann, D.P, Welch, R.C, Kang, C, Smith, J, George, A.L.
登録日2016-06-09
公開日2016-09-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis for KCNE3 modulation of potassium recycling in epithelia.
Sci Adv, 2, 2016
2VS7
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The crystal structure of I-DmoI in complex with DNA and Ca
分子名称: 5'-D(*CP*GP*CP*GP*CP*CP*GP*GP*AP*AP *CP*TP*TP*AP*CP*CP*CP*GP*GP*CP*AP*AP*GP*GP*C)-3', 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP *GP*TP*AP*AP*GP*TP*TP*CP*CP*GP*GP*CP*GP*CP*G)-3', ACETATE ION, ...
著者Marcaida, M.J, Prieto, J, Redondo, P, Nadra, A.D, Alibes, A, Serrano, L, Grizot, S, Duchateau, P, Paques, F, Blanco, F.J, Montoya, G.
登録日2008-04-21
公開日2008-11-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal Structure of I-Dmoi in Complex with its Target DNA Provides New Insights Into Meganuclease Engineering.
Proc.Natl.Acad.Sci.USA, 105, 2008
2VSC
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Structure of the immunoglobulin-superfamily ectodomain of human CD47
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, LEUKOCYTE SURFACE ANTIGEN CD47, MAGNESIUM ION
著者Hatherley, D, Graham, S.C, Turner, J, Harlos, K, Stuart, D.I, Barclay, A.N.
登録日2008-04-22
公開日2008-08-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with Cd47.
Mol.Cell, 31, 2008
2VU9
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CRYSTAL STRUCTURE OF BOTULINUM NEUROTOXIN SEROTYPE A BINDING DOMAIN IN COMPLEX WITH GT1B
分子名称: BOTULINUM NEUROTOXIN A HEAVY CHAIN, MAGNESIUM ION, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Stenmark, P, Dupuy, J, Stevens, R.C.
登録日2008-05-22
公開日2008-08-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of Botulinum Neurotoxin Type a in Complex with the Cell Surface Co-Receptor Gt1B- Insight Into the Toxin-Neuron Interaction.
Plos Pathog., 4, 2008
2W1F
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Structure determination of Aurora Kinase in complex with inhibitor
分子名称: N-[3-(1H-BENZIMIDAZOL-2-YL)-1H-PYRAZOL-4-YL]BENZAMIDE, SERINE/THREONINE-PROTEIN KINASE 6
著者Howard, S, Berdini, V, Boulstridge, J.A, Carr, M.G, Cross, D.M, Curry, J, Devine, L.A, Early, T.R, Fazal, L, Gill, A.L, Heathcote, M, Maman, S, Matthews, J.E, McMenamin, R.L, Navarro, E.F, O'Brien, M.A, O'Reilly, M, Rees, D.C, Reule, M, Tisi, D, Williams, G, Vinkovic, M, Wyatt, P.G.
登録日2008-10-17
公開日2009-01-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Fragment-Based Discovery of the Pyrazol-4-Yl Urea (at9283), a Multitargeted Kinase Inhibitor with Potent Aurora Kinase Activity.
J.Med.Chem., 52, 2009
3RFV
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Crystal structure of Uronate dehydrogenase from Agrobacterium tumefaciens complexed with NADH and product
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, D-galactaro-1,5-lactone, PHOSPHATE ION, ...
著者Parkkinen, T, Rouvinen, J.
登録日2011-04-07
公開日2011-06-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of Uronate Dehydrogenase from Agrobacterium tumefaciens.
J.Biol.Chem., 286, 2011
7KBH
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Structure of Human HDAC2 in complex with a 2-substituted benzamide inhibitor (compound 16)
分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, Histone deacetylase 2, ...
著者Klein, D.J, Liu, J.
登録日2020-10-02
公開日2020-12-30
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Discovery of Highly Selective and Potent HDAC3 Inhibitors Based on a 2-Substituted Benzamide Zinc Binding Group.
Acs Med.Chem.Lett., 11, 2020
4PJ5
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Structure of human MR1-Ac-6-FP in complex with human MAIT TRBV6-1 TCR
分子名称: Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, N-(6-formyl-4-oxo-3,4-dihydropteridin-2-yl)acetamide, ...
著者Birkinshaw, R.W, Rossjohn, J.
登録日2014-05-12
公開日2014-07-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells.
J.Exp.Med., 211, 2014
4FMK
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Crystal structure of mouse nectin-2 extracellular fragment D1-D2
分子名称: CADMIUM ION, Poliovirus receptor-related protein 2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Harrison, O.J, Brasch, J, Shapiro, L.
登録日2012-06-17
公開日2012-08-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Nectin ectodomain structures reveal a canonical adhesive interface.
Nat.Struct.Mol.Biol., 19, 2012
4PJI
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Structure of human MR1-Ac-6-FP in complex with human MAIT C-C10 TCR
分子名称: Beta-2-microglobulin, GLYCEROL, Major histocompatibility complex class I-related gene protein, ...
著者Birkinshaw, R.W, Rossjohn, J.
登録日2014-05-12
公開日2014-07-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells.
J.Exp.Med., 211, 2014
2IZ1
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6PDH complexed with PEX inhibitor synchrotron data
分子名称: 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, 4-PHOSPHO-D-ERYTHRONOHYDROXAMIC ACID, ...
著者Sundaramoorthy, R, Iulek, J, Hunter, W.N.
登録日2006-07-23
公開日2007-01-23
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures of a Bacterial 6- Phosphogluconate Dehydrogenase Reveal Aspects of Specificity, Mechanism and Mode of Inhibition by Analogues of High-Energy Reaction Intermediates.
FEBS J., 274, 2007
6HTJ
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Crystal structure of the translation recovery factor Trf from Sulfolobus solfataricus
分子名称: Nucleic-acid-binding protein containing a Zn-ribbon, ZINC ION
著者Woehnert, J, Pogoryelov, D, Kaiser, M.
登録日2018-10-04
公開日2019-10-16
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of the translation recovery factor Trf from Sulfolobus solfataricus.
Febs Open Bio, 2019
8UNH
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Cryo-EM structure of T4 Bacteriophage Clamp Loader with Sliding Clamp
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Sliding clamp, ...
著者Huang, Y, Marcus, K, Subramanian, S, Gee, L.C, Gorday, K, Ghaffari-Kashani, S, Luo, X, Zhang, L, O'Donnell, M, Subramanian, S, Kuriyan, J.
登録日2023-10-19
公開日2023-12-13
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM.
Nat.Struct.Mol.Biol., 31, 2024
2IZ0
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PEX inhibitor-home data
分子名称: 1,2-ETHANEDIOL, 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ...
著者Sundaramoorthy, R, Iulek, J, Hunter, W.N.
登録日2006-07-23
公開日2007-01-23
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structures of a Bacterial 6- Phosphogluconate Dehydrogenase Reveal Aspects of Specificity, Mechanism and Mode of Inhibition by Analogues of High-Energy Reaction Intermediates.
FEBS J., 274, 2007
4FPR
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Structure of a fungal protein
分子名称: Avirulence Effector AvrLm4-7
著者Blondeau, K, Blaise, F, Graille, M, Linglin, J, Ollivier, B, Labarde, A, Doizy, A, Daverdin, G, Balesdent, M.H, Rouxel, T, van Tilbeurgh, H, Fudal, I.
登録日2012-06-22
公開日2013-12-11
最終更新日2022-08-03
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献Crystal structure of the effector AvrLm4-7 of Leptosphaeria maculans reveals insights into its translocation into plant cells and recognition by resistance proteins.
Plant J., 83, 2015
2NV5
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Crystal structure of a C-terminal phosphatase domain of Rattus norvegicus ortholog of human protein tyrosine phosphatase, receptor type, D (PTPRD)
分子名称: protein-tyrosine-phosphatase
著者Bonanno, J.B, Gilmore, J, Bain, K.T, Iizuka, M, Xu, W, Wasserman, S, Smith, D, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2006-11-10
公開日2006-11-21
最終更新日2024-10-02
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural genomics of protein phosphatases.
J.STRUCT.FUNCT.GENOM., 8, 2007

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