2IZ0

PEX inhibitor-home data

Summary for 2IZ0

Entry DOI	10.2210/pdb2iz0/pdb
Related	2IYO 2IYP 2IZ1
Descriptor	6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 4-PHOSPHO-D-ERYTHRONOHYDROXAMIC ACID, ... (10 entities in total)
Functional Keywords	pentose shunt, oxidoreductase, gluconate utilization, pentose phosphate pathway
Biological source	LACTOCOCCUS LACTIS
Total number of polymer chains	3
Total formula weight	161468.34
Authors	Sundaramoorthy, R.,Iulek, J.,Hunter, W.N. (deposition date: 2006-07-23, release date: 2007-01-23, Last modification date: 2011-07-13)
Primary citation	Sundaramoorthy, R.,Iulek, J.,Barrett, M.P.,Bidet, O.,Ruda, G.F.,Gilbert, I.H.,Hunter, W.N. Crystal Structures of a Bacterial 6- Phosphogluconate Dehydrogenase Reveal Aspects of Specificity, Mechanism and Mode of Inhibition by Analogues of High-Energy Reaction Intermediates. FEBS J., 274:275-, 2007 Cited by PubMed: 17222187 DOI: 10.1111/J.1742-4658.2006.05585.X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation