Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
| A | 0006098 | biological_process | pentose-phosphate shunt |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019521 | biological_process | D-gluconate metabolic process |
| A | 0050661 | molecular_function | NADP binding |
| B | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
| B | 0006098 | biological_process | pentose-phosphate shunt |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019521 | biological_process | D-gluconate metabolic process |
| B | 0050661 | molecular_function | NADP binding |
| C | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
| C | 0006098 | biological_process | pentose-phosphate shunt |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0019521 | biological_process | D-gluconate metabolic process |
| C | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B1471 |
| Chain | Residue |
| B | SER128 |
| B | GLY129 |
| B | ILE367 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL B1472 |
| Chain | Residue |
| B | ASN112 |
| B | GLY144 |
| B | GLN145 |
| B | ASN177 |
| B | HOH2084 |
| B | HOH2274 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL C1471 |
| Chain | Residue |
| C | SER128 |
| C | GLY129 |
| C | HIS187 |
| C | ILE367 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL C1472 |
| Chain | Residue |
| C | ASN112 |
| C | GLY144 |
| C | GLN145 |
| C | ASN177 |
| C | HOH2081 |
| site_id | AC5 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE NAP A1470 |
| Chain | Residue |
| A | GLY10 |
| A | MET11 |
| A | ALA12 |
| A | VAL13 |
| A | MET14 |
| A | ASN33 |
| A | ARG34 |
| A | THR35 |
| A | MET73 |
| A | VAL74 |
| A | GLN75 |
| A | ALA76 |
| A | ALA79 |
| A | GLY101 |
| A | ASN102 |
| A | VAL127 |
| A | LYS184 |
| A | RES1471 |
| A | HOH2484 |
| A | HOH2486 |
| A | HOH2488 |
| A | HOH2489 |
| A | HOH2490 |
| A | HOH2491 |
| A | HOH2492 |
| B | GLY451 |
| site_id | AC6 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE RES A1471 |
| Chain | Residue |
| A | ASN102 |
| A | LYS184 |
| A | ASN188 |
| A | GLU191 |
| A | TYR192 |
| A | ASN261 |
| A | LYS262 |
| A | ARG289 |
| A | NAP1470 |
| A | HOH2219 |
| A | HOH2292 |
| A | HOH2492 |
| A | HOH2493 |
| B | ARG447 |
| B | PHE450 |
| B | HIS453 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE P33 A1473 |
| Chain | Residue |
| A | GLN165 |
| A | GLU371 |
| A | PEG1474 |
| A | HOH2497 |
| A | HOH2498 |
| C | GLN47 |
| C | P331474 |
| C | HOH2584 |
| site_id | AC8 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ATR B1470 |
| Chain | Residue |
| B | ALA12 |
| B | ASN33 |
| B | ARG34 |
| B | THR35 |
| B | LYS38 |
| B | VAL74 |
| B | GLN75 |
| B | ALA79 |
| B | THR83 |
| B | HOH2046 |
| B | HOH2556 |
| B | HOH2557 |
| B | HOH2558 |
| B | HOH2559 |
| B | HOH2560 |
| B | HOH2562 |
| B | HOH2563 |
| B | HOH2564 |
| B | HOH2565 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B1473 |
| Chain | Residue |
| B | GLN444 |
| B | ARG447 |
| B | HIS453 |
| B | THR454 |
| B | HOH2534 |
| B | HOH2567 |
| B | HOH2568 |
| site_id | BC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE ATR C1470 |
| Chain | Residue |
| C | LYS38 |
| C | VAL74 |
| C | GLN75 |
| C | ALA79 |
| C | THR83 |
| C | HOH2016 |
| C | HOH2062 |
| C | HOH2571 |
| C | HOH2572 |
| C | HOH2574 |
| C | GLY10 |
| C | MET11 |
| C | ASN33 |
| C | ARG34 |
| C | THR35 |
| site_id | BC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE P33 C1474 |
| Chain | Residue |
| A | PRO164 |
| A | ASP166 |
| A | P331473 |
| C | PHE43 |
| C | GLN47 |
| C | LYS49 |
| C | LEU51 |
| C | HOH2085 |
| C | HOH2579 |
| C | HOH2582 |
| C | HOH2583 |
| C | HOH2584 |
| site_id | BC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A1472 |
| Chain | Residue |
| A | GLU23 |
| A | SER24 |
| A | LYS49 |
| A | ASN50 |
| A | HOH2494 |
| A | HOH2495 |
| A | HOH2496 |
| C | ARG25 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG A1474 |
| Chain | Residue |
| A | P331473 |
| A | HOH2500 |
| C | HOH2584 |
| site_id | BC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL C1473 |
| Chain | Residue |
| C | PRO278 |
| C | PRO280 |
| C | ALA288 |
| C | ILE291 |
| C | SER428 |
| C | TYR429 |
| C | SER432 |
| C | HOH2378 |
| C | HOH2379 |
| C | HOH2578 |
Functional Information from PROSITE/UniProt
| site_id | PS00461 |
| Number of Residues | 13 |
| Details | 6PGD 6-phosphogluconate dehydrogenase signature. IlDkaGNKGTGkW |
| Chain | Residue | Details |
| A | ILE255-TRP267 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"17222187","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"17222187","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 33 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17222187","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 20 |
| Details | Binding site: {"description":"in other chain","evidences":[{"source":"PubMed","id":"17222187","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 2pgd |
| Chain | Residue | Details |
| A | GLY130 | |
| A | GLU191 | |
| A | LYS184 | |
| A | ASN188 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 2pgd |
| Chain | Residue | Details |
| B | GLY130 | |
| B | GLU191 | |
| B | LYS184 | |
| B | ASN188 | |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 2pgd |
| Chain | Residue | Details |
| C | GLY130 | |
| C | GLU191 | |
| C | LYS184 | |
| C | ASN188 | |
