8UNH

Cryo-EM structure of T4 Bacteriophage Clamp Loader with Sliding Clamp

Summary for 8UNH

• Entry DOI: 10.2210/pdb8unh/pdb
• Related: 8UNF
• EMDB information: 42399 42402
• Descriptor: Sliding-clamp-loader large subunit, Sliding-clamp-loader small subunit, Sliding clamp, ... (5 entities in total)
• Functional Keywords: autoinhibited, dna-free, catalytically inactive, stable, replication
• Biological source: Tequatrovirus T4; More
• Total number of polymer chains: 8
• Total formula weight: 240467.49

Authors

Huang, Y.,Marcus, K.,Subramanian, S.,Gee, L.C.,Gorday, K.,Ghaffari-Kashani, S.,Luo, X.,Zhang, L.,O'Donnell, M.,Subramanian, S.,Kuriyan, J. (deposition date: 2023-10-19, release date: 2023-12-13, Last modification date: 2024-04-03)

• Primary citation: Marcus, K.,Huang, Y.,Subramanian, S.,Gee, C.L.,Gorday, K.,Ghaffari-Kashani, S.,Luo, X.R.,Zheng, L.,O'Donnell, M.,Subramaniam, S.,Kuriyan, J.; Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM.; Nat.Struct.Mol.Biol., 31:424-435, 2024; PubMed: 38177685; DOI: 10.1038/s41594-023-01177-3

Experimental method

ELECTRON MICROSCOPY (3.21 Å)