2VU9

CRYSTAL STRUCTURE OF BOTULINUM NEUROTOXIN SEROTYPE A BINDING DOMAIN IN COMPLEX WITH GT1B

Summary for 2VU9

Entry DOI	10.2210/pdb2vu9/pdb
Related	1UEE 2VUA 3BTA
Descriptor	BOTULINUM NEUROTOXIN A HEAVY CHAIN, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	hydrolase, metalloprotease, neurotoxin, ganglioside, metal-binding, toxin, protease, membrane, receptor, secreted
Biological source	CLOSTRIDIUM BOTULINUM
Total number of polymer chains	1
Total formula weight	53027.84
Authors	Stenmark, P.,Dupuy, J.,Stevens, R.C. (deposition date: 2008-05-22, release date: 2008-08-26, Last modification date: 2023-12-13)
Primary citation	Stenmark, P.,Dupuy, J.,Imamura, A.,Kiso, M.,Stevens, R.C. Crystal Structure of Botulinum Neurotoxin Type a in Complex with the Cell Surface Co-Receptor Gt1B- Insight Into the Toxin-Neuron Interaction. Plos Pathog., 4:E129-, 2008 Cited by PubMed: 18704164 DOI: 10.1371/JOURNAL.PPAT.1000129 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation