2VSC

Structure of the immunoglobulin-superfamily ectodomain of human CD47

Summary for 2VSC

Related2JJS 2JJT
DescriptorLEUKOCYTE SURFACE ANTIGEN CD47, N-ACETYL-D-GLUCOSAMINE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordsimmunoglobulin domain, signal regulatory protein, cd47, membrane, glycoprotein, cell adhesion, immunoglobulin superfamily, pyrrolidone carboxylic acid, transmembrane, paired receptor, alternative splicing
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains4
Total molecular weight60776.31
Authors
Hatherley, D.,Graham, S.C.,Turner, J.,Harlos, K.,Stuart, D.I.,Barclay, A.N. (deposition date: 2008-04-22, release date: 2008-08-12, Last modification date: 2019-04-03)
Primary citation
Hatherley, D.,Graham, S.C.,Turner, J.,Harlos, K.,Stuart, D.I.,Barclay, A.N.
Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with Cd47.
Mol.Cell, 31:266-, 2008
PubMed: 18657508 (PDB entries with the same primary citation)
DOI: 10.1016/J.MOLCEL.2008.05.026
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.26540 1.0% 3.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution