2VSC
Structure of the immunoglobulin-superfamily ectodomain of human CD47
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | LEUKOCYTE SURFACE ANTIGEN CD47 | polymer | 127 | 14518.3 | 4 | UniProt (Q08722) Pfam (PF08204) | HOMO SAPIENS (HUMAN) | INTEGRIN-ASSOCIATED PROTEIN, IAP, ANTIGENIC SURFACE DETERMINANT PROTEIN OA3, PROTEIN MER6, CD47 |
| 2 | E, F, G, H, J... (A, B, C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) | |||
| 3 | I, P (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | S, T, U, V (A, B, C, D) | water | water | 18.0 | 353 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 118 (UniProt: Q08722)
A, B, C, D: 119 - 127 (PDB: 2VSC)
| PDB | External Database | Details |
|---|---|---|
| Gly 15 | Cys 33 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 58073.2 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2703.1 | |
| All* | Total formula weight | 60776.3 |






