2VSC

Structure of the immunoglobulin-superfamily ectodomain of human CD47

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Functional Information from GO Data

ChainGOidnamespacecontents
A0009986cellular_componentcell surface
A0070062cellular_componentextracellular exosome
A0005887cellular_componentintegral component of plasma membrane
A0005886cellular_componentplasma membrane
A0035579cellular_componentspecific granule membrane
A0070821cellular_componenttertiary granule membrane
A0098632molecular_functioncell-cell adhesion mediator activity
A0086080molecular_functionprotein binding involved in heterotypic cell-cell adhesion
A0070053molecular_functionthrombospondin receptor activity
A0016477biological_processcell migration
A0071346biological_processcellular response to interferon-gamma
A0071347biological_processcellular response to interleukin-1
A0071349biological_processcellular response to interleukin-12
A0030198biological_processextracellular matrix organization
A0006954biological_processinflammatory response
A0007229biological_processintegrin-mediated signaling pathway
A0050900biological_processleukocyte migration
A0070487biological_processmonocyte aggregation
A0035696biological_processmonocyte extravasation
A1905450biological_processnegative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
A0043312biological_processneutrophil degranulation
A0008228biological_processopsonization
A0008284biological_processpositive regulation of cell proliferation
A0022409biological_processpositive regulation of cell-cell adhesion
A0050729biological_processpositive regulation of inflammatory response
A0050766biological_processpositive regulation of phagocytosis
A0051496biological_processpositive regulation of stress fiber assembly
A0050870biological_processpositive regulation of T cell activation
A0032649biological_processregulation of interferon-gamma production
A0032653biological_processregulation of interleukin-10 production
A0032655biological_processregulation of interleukin-12 production
A0032675biological_processregulation of interleukin-6 production
A0045428biological_processregulation of nitric oxide biosynthetic process
A0032680biological_processregulation of tumor necrosis factor production
A0009617biological_processresponse to bacterium
B0009986cellular_componentcell surface
B0070062cellular_componentextracellular exosome
B0005887cellular_componentintegral component of plasma membrane
B0005886cellular_componentplasma membrane
B0035579cellular_componentspecific granule membrane
B0070821cellular_componenttertiary granule membrane
B0098632molecular_functioncell-cell adhesion mediator activity
B0086080molecular_functionprotein binding involved in heterotypic cell-cell adhesion
B0070053molecular_functionthrombospondin receptor activity
B0016477biological_processcell migration
B0071346biological_processcellular response to interferon-gamma
B0071347biological_processcellular response to interleukin-1
B0071349biological_processcellular response to interleukin-12
B0030198biological_processextracellular matrix organization
B0006954biological_processinflammatory response
B0007229biological_processintegrin-mediated signaling pathway
B0050900biological_processleukocyte migration
B0070487biological_processmonocyte aggregation
B0035696biological_processmonocyte extravasation
B1905450biological_processnegative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
B0043312biological_processneutrophil degranulation
B0008228biological_processopsonization
B0008284biological_processpositive regulation of cell proliferation
B0022409biological_processpositive regulation of cell-cell adhesion
B0050729biological_processpositive regulation of inflammatory response
B0050766biological_processpositive regulation of phagocytosis
B0051496biological_processpositive regulation of stress fiber assembly
B0050870biological_processpositive regulation of T cell activation
B0032649biological_processregulation of interferon-gamma production
B0032653biological_processregulation of interleukin-10 production
B0032655biological_processregulation of interleukin-12 production
B0032675biological_processregulation of interleukin-6 production
B0045428biological_processregulation of nitric oxide biosynthetic process
B0032680biological_processregulation of tumor necrosis factor production
B0009617biological_processresponse to bacterium
C0009986cellular_componentcell surface
C0070062cellular_componentextracellular exosome
C0005887cellular_componentintegral component of plasma membrane
C0005886cellular_componentplasma membrane
C0035579cellular_componentspecific granule membrane
C0070821cellular_componenttertiary granule membrane
C0098632molecular_functioncell-cell adhesion mediator activity
C0086080molecular_functionprotein binding involved in heterotypic cell-cell adhesion
C0070053molecular_functionthrombospondin receptor activity
C0016477biological_processcell migration
C0071346biological_processcellular response to interferon-gamma
C0071347biological_processcellular response to interleukin-1
C0071349biological_processcellular response to interleukin-12
C0030198biological_processextracellular matrix organization
C0006954biological_processinflammatory response
C0007229biological_processintegrin-mediated signaling pathway
C0050900biological_processleukocyte migration
C0070487biological_processmonocyte aggregation
C0035696biological_processmonocyte extravasation
C1905450biological_processnegative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
C0043312biological_processneutrophil degranulation
C0008228biological_processopsonization
C0008284biological_processpositive regulation of cell proliferation
C0022409biological_processpositive regulation of cell-cell adhesion
C0050729biological_processpositive regulation of inflammatory response
C0050766biological_processpositive regulation of phagocytosis
C0051496biological_processpositive regulation of stress fiber assembly
C0050870biological_processpositive regulation of T cell activation
C0032649biological_processregulation of interferon-gamma production
C0032653biological_processregulation of interleukin-10 production
C0032655biological_processregulation of interleukin-12 production
C0032675biological_processregulation of interleukin-6 production
C0045428biological_processregulation of nitric oxide biosynthetic process
C0032680biological_processregulation of tumor necrosis factor production
C0009617biological_processresponse to bacterium
D0009986cellular_componentcell surface
D0070062cellular_componentextracellular exosome
D0005887cellular_componentintegral component of plasma membrane
D0005886cellular_componentplasma membrane
D0035579cellular_componentspecific granule membrane
D0070821cellular_componenttertiary granule membrane
D0098632molecular_functioncell-cell adhesion mediator activity
D0086080molecular_functionprotein binding involved in heterotypic cell-cell adhesion
D0070053molecular_functionthrombospondin receptor activity
D0016477biological_processcell migration
D0071346biological_processcellular response to interferon-gamma
D0071347biological_processcellular response to interleukin-1
D0071349biological_processcellular response to interleukin-12
D0030198biological_processextracellular matrix organization
D0006954biological_processinflammatory response
D0007229biological_processintegrin-mediated signaling pathway
D0050900biological_processleukocyte migration
D0070487biological_processmonocyte aggregation
D0035696biological_processmonocyte extravasation
D1905450biological_processnegative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
D0043312biological_processneutrophil degranulation
D0008228biological_processopsonization
D0008284biological_processpositive regulation of cell proliferation
D0022409biological_processpositive regulation of cell-cell adhesion
D0050729biological_processpositive regulation of inflammatory response
D0050766biological_processpositive regulation of phagocytosis
D0051496biological_processpositive regulation of stress fiber assembly
D0050870biological_processpositive regulation of T cell activation
D0032649biological_processregulation of interferon-gamma production
D0032653biological_processregulation of interleukin-10 production
D0032655biological_processregulation of interleukin-12 production
D0032675biological_processregulation of interleukin-6 production
D0045428biological_processregulation of nitric oxide biosynthetic process
D0032680biological_processregulation of tumor necrosis factor production
D0009617biological_processresponse to bacterium
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Functional Information from PDB Data

site_idNumber of ResiduesDetails
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Functional Information from PDB atom coordinates for the "HETATM" binding sites

site_idNumber of ResiduesDetails
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Functional Information from PROSITE/UniProt

site_idNumber of ResiduesDetails
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Functional Information from SwissProt/UniProt

site_idNumber of ResiduesDetails
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Catalytic Information from CSA

site_idNumber of ResiduesDetails
167327
PDB entries from 2020-08-05