3R0F
Human enterovirus 71 3C protease mutant H133G in complex with rupintrivir
Summary for 3R0F
Entry DOI | 10.2210/pdb3r0f/pdb |
Related | 3OSY |
Descriptor | 3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | chymotrypsin-fold, beta-ribbon, hydrolysis, nucleus, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Human enterovirus 71 |
Total number of polymer chains | 2 |
Total formula weight | 42492.65 |
Authors | |
Primary citation | Wang, J.,Fan, T.,Yao, X.,Wu, Z.,Guo, L.,Lei, X.,Wang, J.,Wang, M.,Jin, Q.,Cui, S. Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues. J.Virol., 85:10021-10030, 2011 Cited by PubMed: 21813612DOI: 10.1128/JVI.05107-11 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3083 Å) |
Structure validation
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