4QP2
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6XWV
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![BU of 6xwv by Molmil](/molmil-images/mine/6xwv) | Crystal structure of drosophila melanogaster CENP-C bound to CAL1 | 分子名称: | Calmodulin, Ryanodine Receptor 2 | 著者 | Jeyaprakash, A.A, Medina-Pritchard, B, Lazou, V, Zou, J, Byron, O, Abad, M.A, Rappsilber, J, Heun, P. | 登録日 | 2020-01-24 | 公開日 | 2020-04-01 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Structural basis for centromere maintenance by Drosophila CENP-A chaperone CAL1. Embo J., 39, 2020
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6XWT
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![BU of 6xwt by Molmil](/molmil-images/mine/6xwt) | drosophila melanogaster CENP-A/H4 bound to N-terminal CAL1 fragment | 分子名称: | Chromosome alignment defect 1, Histone H3-like centromeric protein cid, Histone H4 | 著者 | Jeyaprakash, A.A, Medina-Pritchard, B, Lazou, V, Zou, J, Byron, O, Abad, M.A, Rappsilber, J, Heun, P. | 登録日 | 2020-01-24 | 公開日 | 2020-04-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.47 Å) | 主引用文献 | Structural basis for centromere maintenance by Drosophila CENP-A chaperone CAL1. Embo J., 39, 2020
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6XK9
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![BU of 6xk9 by Molmil](/molmil-images/mine/6xk9) | Cereblon in complex with DDB1, CC-90009, and GSPT1 | 分子名称: | 2-(4-chlorophenyl)-N-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)-2,2-difluoroacetamide, DNA damage-binding protein 1, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, ... | 著者 | Clayton, T.L, Tran, E.T, Zhu, J, Pagarigan, B.E, Matyskiela, M.E, Chamberlain, P.P. | 登録日 | 2020-06-25 | 公開日 | 2020-12-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.64 Å) | 主引用文献 | CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells. Blood, 137, 2021
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5MG0
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![BU of 5mg0 by Molmil](/molmil-images/mine/5mg0) | Structure of PAS-GAF fragment of Deinococcus phytochrome by serial femtosecond crystallography | 分子名称: | 1,2-ETHANEDIOL, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome, ... | 著者 | Burgie, E.S, Fuller, F.D, Gul, S, Miller, M.D, Young, I.D, Brewster, A.S, Clinger, J, Aller, P, Braeuer, P, Hutchison, C, Alonso-Mori, R, Kern, J, Yachandra, V.K, Yano, J, Sauter, N.K, Phillips Jr, G.N, Vierstra, R.D, Orville, A.M. | 登録日 | 2016-11-20 | 公開日 | 2017-02-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Drop-on-demand sample delivery for studying biocatalysts in action at X-ray free-electron lasers. Nat. Methods, 14, 2017
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6XFP
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![BU of 6xfp by Molmil](/molmil-images/mine/6xfp) | Crystal Structure of BRAF kinase domain bound to Belvarafenib | 分子名称: | 4-amino-N-{1-[(3-chloro-2-fluorophenyl)amino]-6-methylisoquinolin-5-yl}thieno[3,2-d]pyrimidine-7-carboxamide, CHLORIDE ION, Serine/threonine-protein kinase B-raf | 著者 | Yin, J, Sudhamsu, J. | 登録日 | 2020-06-16 | 公開日 | 2021-03-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | ARAF mutations confer resistance to the RAF inhibitor belvarafenib in melanoma. Nature, 594, 2021
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6U60
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![BU of 6u60 by Molmil](/molmil-images/mine/6u60) | Crystal structure of prephenate dehydrogenase tyrA from Bacillus anthracis in complex with NAD and L-tyrosine | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION, Prephenate dehydrogenase, ... | 著者 | Shabalin, I.G, Hou, J, Kutner, J, Grimshaw, S, Christendat, D, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-08-28 | 公開日 | 2019-09-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain. Febs J., 287, 2020
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7MFV
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![BU of 7mfv by Molmil](/molmil-images/mine/7mfv) | Crystal structure of synthetic nanobody (Sb16) | 分子名称: | 1,2-ETHANEDIOL, Synthetic Nanobody #16 (Sb16) | 著者 | Jiang, J, Ahmad, J, Natarajan, K, Boyd, L.F, Margulies, D.H. | 登録日 | 2021-04-11 | 公開日 | 2021-06-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction. J.Biol.Chem., 297, 2021
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5GZO
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![BU of 5gzo by Molmil](/molmil-images/mine/5gzo) | Structure of neutralizing antibody bound to Zika envelope protein | 分子名称: | Antibody heavy chain, Antibody light chain, Genome polyprotein | 著者 | Wang, Q, Yang, H, Liu, X, Dai, L, Ma, T, Qi, J, Wong, G, Peng, R, Liu, S, Li, J, Li, S, Song, J, Liu, J, He, J, Yuan, H, Xiong, Y, Liao, Y, Li, J, Yang, J, Tong, Z, Griffin, B, Bi, Y, Liang, M, Xu, X, Cheng, G, Wang, P, Qiu, X, Kobinger, G, Shi, Y, Yan, J, Gao, G.F. | 登録日 | 2016-09-29 | 公開日 | 2017-01-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.755 Å) | 主引用文献 | Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus Sci Transl Med, 8, 2016
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5M62
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![BU of 5m62 by Molmil](/molmil-images/mine/5m62) | Structure of the Mus musclus Langerin carbohydrate recognition domain in complex with glucose | 分子名称: | C-type lectin domain family 4 member K, CALCIUM ION, GLYCEROL, ... | 著者 | Loll, B, Aretz, J, Rademacher, C, Wahl, M.C. | 登録日 | 2016-10-24 | 公開日 | 2016-12-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Bacterial Polysaccharide Specificity of the Pattern Recognition Receptor Langerin Is Highly Species-dependent. J. Biol. Chem., 292, 2017
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5MG1
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![BU of 5mg1 by Molmil](/molmil-images/mine/5mg1) | Structure of the photosensory module of Deinococcus phytochrome by serial femtosecond X-ray crystallography | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome | 著者 | Burgie, E.S, Fuller, F.D, Gul, S, Young, I.D, Brewster, A.S, Clinger, J, Andi, B, Stan, C, Allaire, M, Nelsen, S, Alonso-Mori, R, Phillips Jr, G.N, Sauter, N.K, Kern, J, Yachandra, V.K, Yano, J, Vierstra, R.D, Orville, A.M. | 登録日 | 2016-11-20 | 公開日 | 2017-02-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Drop-on-demand sample delivery for studying biocatalysts in action at X-ray free-electron lasers. Nat. Methods, 14, 2017
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6UKJ
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![BU of 6ukj by Molmil](/molmil-images/mine/6ukj) | Single-Particle Cryo-EM Structure of Plasmodium falciparum Chloroquine Resistance Transporter (PfCRT) 7G8 Isoform | 分子名称: | CHOLESTEROL HEMISUCCINATE, Chloroquine resistance transporter, Fab Heavy Chain, ... | 著者 | Kim, J, Tan, Y.Z, Wicht, K.J, Erramilli, S.K, Dhingra, S.K, Okombo, J, Vendome, J, Hagenah, L.M, Giacometti, S.I, Warren, A.L, Nosol, K, Roepe, P.D, Potter, C.S, Carragher, B, Kossiakoff, A.A, Quick, M, Fidock, D.A, Mancia, F. | 登録日 | 2019-10-05 | 公開日 | 2019-12-04 | 最終更新日 | 2020-01-08 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure and drug resistance of the Plasmodium falciparum transporter PfCRT. Nature, 576, 2019
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6XP6
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![BU of 6xp6 by Molmil](/molmil-images/mine/6xp6) | 3C11-DQ2-glia-a2 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3.C11 IgH Fab, ... | 著者 | Petersen, J, Rossjohn, J. | 登録日 | 2020-07-08 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A high-affinity human TCR-like antibody detects celiac disease gluten peptide-MHC complexes and inhibits T cell activation. Sci Immunol, 6, 2021
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6XNG
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![BU of 6xng by Molmil](/molmil-images/mine/6xng) | MHC-like protein complex structure | 分子名称: | (3R)-N-[(2S,3R)-1-(alpha-D-galactopyranosyloxy)-3-hydroxyheptadecan-2-yl]-3-hydroxyheptadecanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | 著者 | Thirunavukkarasu, P, Le Nours, J, Rossjohn, J. | 登録日 | 2020-07-02 | 公開日 | 2021-11-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Host immunomodulatory lipids created by symbionts from dietary amino acids. Nature, 600, 2021
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8GOB
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![BU of 8gob by Molmil](/molmil-images/mine/8gob) | Crystal Structure of Glycerol Dehydrogenase in the presence of NAD+ | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glycerol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Park, T, Hoang, H.N, Kang, J.Y, Park, J, Mun, S.A, Jin, M, Yang, J, Jung, C.-H, Eom, S.H. | 登録日 | 2022-08-24 | 公開日 | 2023-06-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural and functional insights into the flexible beta-hairpin of glycerol dehydrogenase. Febs J., 290, 2023
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8GOA
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![BU of 8goa by Molmil](/molmil-images/mine/8goa) | Crystal Structure of Glycerol Dehydrogenase in the absence of NAD+ | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glycerol dehydrogenase, ZINC ION | 著者 | Park, T, Hoang, H.N, Kang, J.Y, Park, J, Mun, S.A, Jin, M, Yang, J, Jung, C.-H, Eom, S.H. | 登録日 | 2022-08-24 | 公開日 | 2023-06-14 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural and functional insights into the flexible beta-hairpin of glycerol dehydrogenase. Febs J., 290, 2023
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5CNA
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![BU of 5cna by Molmil](/molmil-images/mine/5cna) | REFINED STRUCTURE OF CONCANAVALIN A COMPLEXED WITH ALPHA-METHYL-D-MANNOPYRANOSIDE AT 2.0 ANGSTROMS RESOLUTION AND COMPARISON WITH THE SACCHARIDE-FREE STRUCTURE | 分子名称: | CALCIUM ION, CHLORIDE ION, CONCANAVALIN A, ... | 著者 | Naismith, J.H, Emmerich, C, Habash, J, Harrop, S.J, Helliwell, J.R, Hunter, W.N, Raftery, J, Kalb(Gilboa), A.J, Yariv, J. | 登録日 | 1994-02-11 | 公開日 | 1994-05-31 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Refined structure of concanavalin A complexed with methyl alpha-D-mannopyranoside at 2.0 A resolution and comparison with the saccharide-free structure. Acta Crystallogr.,Sect.D, 50, 1994
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8AAE
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![BU of 8aae by Molmil](/molmil-images/mine/8aae) | CAII in complex with para-carboran-propylsulfonamid | 分子名称: | Carbonic anhydrase 2, Para-Carborane propyl-sulfonamide, ZINC ION | 著者 | Brynda, J, Rezacova, P. | 登録日 | 2022-07-01 | 公開日 | 2023-05-10 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | B-H⋯ pi and C-H⋯ pi interactions in protein-ligand complexes: carbonic anhydrase II inhibition by carborane sulfonamides. Phys Chem Chem Phys, 25, 2023
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8AA6
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8AZW
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![BU of 8azw by Molmil](/molmil-images/mine/8azw) | Cryo-EM structure of the plant 60S subunit | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Smirnova, J, Loerke, J, Kleinau, G, Schmidt, A, Buerger, J, Meyer, E.H, Mielke, T, Scheerer, P, Bock, R, Spahn, C.M.T, Zoschke, R. | 登録日 | 2022-09-06 | 公開日 | 2023-06-07 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.14 Å) | 主引用文献 | Structure of the actively translating plant 80S ribosome at 2.2 angstrom resolution. Nat.Plants, 9, 2023
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8AUV
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![BU of 8auv by Molmil](/molmil-images/mine/8auv) | Cryo-EM structure of the plant 40S subunit | 分子名称: | 18S rRNA, MAGNESIUM ION, POTASSIUM ION, ... | 著者 | Smirnova, J, Loerke, J, Kleinau, G, Schmidt, A, Buerger, J, Meyer, E.H, Mielke, T, Scheerer, P, Bock, R, Spahn, C.M.T, Zoschke, R. | 登録日 | 2022-08-25 | 公開日 | 2023-06-07 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.38 Å) | 主引用文献 | Structure of the actively translating plant 80S ribosome at 2.2 angstrom resolution. Nat.Plants, 9, 2023
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4R8W
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![BU of 4r8w by Molmil](/molmil-images/mine/4r8w) | Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a neutralizing antibody CT149 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of neutralizing antibody CT149, Hemagglutinin, ... | 著者 | Wu, Y, Shi, Y, Qi, J, Gao, G.F. | 登録日 | 2014-09-03 | 公開日 | 2015-08-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.795 Å) | 主引用文献 | A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus Nat Commun, 6, 2015
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8KD5
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![BU of 8kd5 by Molmil](/molmil-images/mine/8kd5) | Rpd3S in complex with nucleosome with H3K36MLA modification and 187bp DNA, class2 | 分子名称: | 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ... | 著者 | Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Chang, X, Chao, W.C.H, He, J. | 登録日 | 2023-08-09 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex. Cell Res., 33, 2023
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8KD6
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![BU of 8kd6 by Molmil](/molmil-images/mine/8kd6) | Rpd3S in complex with nucleosome with H3K36MLA modification and 187bp DNA, class3 | 分子名称: | 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ... | 著者 | Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Zhang, X, Chao, W.C.H, He, J. | 登録日 | 2023-08-09 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex. Cell Res., 33, 2023
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8KD3
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![BU of 8kd3 by Molmil](/molmil-images/mine/8kd3) | Rpd3S in complex with nucleosome with H3K36MLA modification, H3K9Q mutation and 187bp DNA | 分子名称: | 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ... | 著者 | Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Zhang, X, Chao, W.C.H, He, J. | 登録日 | 2023-08-09 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex. Cell Res., 33, 2023
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