8KD3

Rpd3S in complex with nucleosome with H3K36MLA modification, H3K9Q mutation and 187bp DNA

This is a non-PDB format compatible entry.

Summary for 8KD3

• Entry DOI: 10.2210/pdb8kd3/pdb
• EMDB information: 37123
• Descriptor: Histone deacetylase RPD3, 187bp DNA, ZINC ION, ... (11 entities in total)
• Functional Keywords: rpd3s, hdac, hho1, cryptic transcription, transcription
• Biological source: Saccharomyces cerevisiae (baker's yeast); More
• Total number of polymer chains: 16
• Total formula weight: 708284.93

Authors

Dong, S.,Li, H.,Wang, M.,Rasheed, N.,Zou, B.,Gao, X.,Guan, J.,Li, W.,Zhang, J.,Wang, C.,Zhou, N.,Shi, X.,Li, M.,Zhou, M.,Huang, J.,Li, H.,Zhang, Y.,Wong, K.H.,Zhang, X.,Chao, W.C.H.,He, J. (deposition date: 2023-08-09, release date: 2023-09-13, Last modification date: 2023-10-11)

• Primary citation: Dong, S.,Li, H.,Wang, M.,Rasheed, N.,Zou, B.,Gao, X.,Guan, J.,Li, W.,Zhang, J.,Wang, C.,Zhou, N.,Shi, X.,Li, M.,Zhou, M.,Huang, J.,Li, H.,Zhang, Y.,Wong, K.H.,Zhang, X.,Chao, W.C.H.,He, J.; Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex.; Cell Res., 33:790-801, 2023; PubMed: 37666978; DOI: 10.1038/s41422-023-00869-1

Experimental method

ELECTRON MICROSCOPY (2.9 Å)