6XP6

3C11-DQ2-glia-a2 complex

Summary for 6XP6

• Entry DOI: 10.2210/pdb6xp6/pdb
• Descriptor: MHC class II HLA-DQ-alpha chain, ISOPROPYL ALCOHOL, CHLORIDE ION, ... (12 entities in total)
• Functional Keywords: complex antibody human leucocyte antigen, peptide binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 10
• Total formula weight: 192975.41

Authors

Petersen, J.,Rossjohn, J. (deposition date: 2020-07-08, release date: 2021-07-28, Last modification date: 2023-10-18)

• Primary citation: Frick, R.,Hoydahl, L.S.,Petersen, J.,du Pre, M.F.,Kumari, S.,Berntsen, G.,Dewan, A.E.,Jeliazkov, J.R.,Gunnarsen, K.S.,Frigstad, T.,Vik, E.S.,Llerena, C.,Lundin, K.E.A.,Yaqub, S.,Jahnsen, J.,Gray, J.J.,Rossjohn, J.,Sollid, L.M.,Sandlie, I.,Loset, G.A.; A high-affinity human TCR-like antibody detects celiac disease gluten peptide-MHC complexes and inhibits T cell activation.; Sci Immunol, 6:-, 2021; PubMed: 34417258; DOI: 10.1126/sciimmunol.abg4925

Experimental method

X-RAY DIFFRACTION (2.4 Å)