8CX6
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![BU of 8cx6 by Molmil](/molmil-images/mine/8cx6) | TPX2 Minimal Active Domain on Microtubules | Descriptor: | Targeting protein for Xklp2-A | Authors: | Guo, C, Alfaro-Aco, R, Russell, R, Zhang, C, Petry, S, Polenova, T. | Deposit date: | 2022-05-19 | Release date: | 2023-06-28 | Last modified: | 2024-05-15 | Method: | SOLID-STATE NMR | Cite: | Structural basis of protein condensation on microtubules underlying branching microtubule nucleation. Nat Commun, 14, 2023
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6LNW
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![BU of 6lnw by Molmil](/molmil-images/mine/6lnw) | Crystal structure of accessory secretory protein 1,2 and 3 in Streptococcus pneumoniae | Descriptor: | Accessory secretory protein Asp1, Accessory secretory protein Asp2, Accessory secretory protein Asp3 | Authors: | Guo, C, Feng, Z, Zuo, G. | Deposit date: | 2020-01-02 | Release date: | 2020-02-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural and functional insights into the Asp1/2/3 complex mediated secretion of pneumococcal serine-rich repeat protein PsrP. Biochem.Biophys.Res.Commun., 524, 2020
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2C0G
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![BU of 2c0g by Molmil](/molmil-images/mine/2c0g) | Structure of PDI-related Chaperone, Wind mutant-Y53S | Descriptor: | CHLORIDE ION, SODIUM ION, WINDBEUTEL PROTEIN | Authors: | Sevvana, M, Ma, Q, Barnewitz, K, Guo, C, Soling, H.-D, Ferrari, D.M, Sheldrick, G.M. | Deposit date: | 2005-09-02 | Release date: | 2006-08-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural Elucidation of the Pdi-Related Chaperone Wind with the Help of Mutants. Acta Crystallogr.,Sect.D, 62, 2006
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2C0F
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![BU of 2c0f by Molmil](/molmil-images/mine/2c0f) | Structure of Wind Y53F mutant | Descriptor: | WINDBEUTEL PROTEIN | Authors: | Sevvana, M, Ma, Q, Barnewitz, K, Guo, C, Soling, H.-D, Ferrari, D.M, Sheldrick, G.M. | Deposit date: | 2005-09-02 | Release date: | 2006-08-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structural Elucidation of the Pdi-Related Chaperone Wind with the Help of Mutants. Acta Crystallogr.,Sect.D, 62, 2006
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2C0E
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![BU of 2c0e by Molmil](/molmil-images/mine/2c0e) | Structure of PDI-related Chaperone, Wind with his-tag on C-terminus. | Descriptor: | WINDBEUTEL PROTEIN | Authors: | Sevvana, M, Ma, Q, Barnewitz, K, Guo, C, Soling, H.-D, Ferrari, D.M, Sheldrick, G.M. | Deposit date: | 2005-09-01 | Release date: | 2006-08-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural Elucidation of the Pdi-Related Chaperone Wind with the Help of Mutants. Acta Crystallogr.,Sect.D, 62, 2006
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2C1Y
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![BU of 2c1y by Molmil](/molmil-images/mine/2c1y) | Structure of PDI-related Chaperone, Wind mutant-Y55K | Descriptor: | WINDBEUTEL PROTEIN | Authors: | Sevvana, M, Ma, Q, Barnewitz, K, Guo, C, Soling, H.-D, Ferrari, D.M, Sheldrick, G.M. | Deposit date: | 2005-09-22 | Release date: | 2006-08-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural Elucidation of the Pdi-Related Chaperone Wind with the Help of Mutants. Acta Crystallogr.,Sect.D, 62, 2006
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7RIK
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![BU of 7rik by Molmil](/molmil-images/mine/7rik) | Magic-Angle-Spinning NMR Structure of Kinesin-1 Motor Domain Assembled with Microtubules | Descriptor: | Kinesin-1 heavy chain | Authors: | Zhang, C, Guo, C, Russell, R.W, Quinn, C.M, Li, M, Williams, J.C, Gronenborn, A.M, Polenova, T. | Deposit date: | 2021-07-20 | Release date: | 2022-11-23 | Last modified: | 2024-05-15 | Method: | SOLID-STATE NMR | Cite: | Magic-angle-spinning NMR structure of the kinesin-1 motor domain assembled with microtubules reveals the elusive neck linker orientation Nat Commun, 13, 2022
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1OVN
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![BU of 1ovn by Molmil](/molmil-images/mine/1ovn) | Crystal Structure and Functional Analysis of Drosophila Wind-- a PDI-Related Protein | Descriptor: | CESIUM ION, Windbeutel | Authors: | Ma, Q, Guo, C, Barnewitz, K, Sheldrick, G.M, Soling, H.D, Uson, I, Ferrari, D.M. | Deposit date: | 2003-03-27 | Release date: | 2004-02-24 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure and functional analysis of Drosophila Wind, a protein-disulfide isomerase-related protein. J.Biol.Chem., 278, 2003
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4APP
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![BU of 4app by Molmil](/molmil-images/mine/4app) | Crystal Structure of the Human p21-Activated Kinase 4 in Complex with (S)-N-(5-(3-benzyl-1-methylpiperazine-4-carbonyl)-6,6-dimethyl-1,4,5, 6-tetrahydropyrrolo(3,4-c)pyrazol-3-yl)-3-phenoxybenzamide | Descriptor: | GLYCEROL, N-[6,6-dimethyl-5-[(2S)-4-methyl-2-(phenylmethyl)piperazin-1-yl]carbonyl-2,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]-3-phenoxy-benzamide, SERINE/THREONINE-PROTEIN KINASE PAK 4 | Authors: | Knighton, D.D, Deng, Y.L, Wang, C, Guo, C, McAlpine, I, Zhang, J, Kephart, S, Johnson, M.C, Li, H, Bouzida, D, Yang, A, Dong, L, Marakovits, J, Tikhe, J, Richardson, P, Guo, L.C, Kania, R, Edwards, M.P, Kraynov, E, Christensen, J, Piraino, J, Lee, J, Dagostino, E, Del-Carmen, C, Smeal, T, Murray, B.W. | Deposit date: | 2012-04-04 | Release date: | 2012-06-06 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Discovery of Pyrroloaminopyrazoles as Novel Pak Inhibitors. J.Med.Chem., 55, 2012
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2X4Z
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![BU of 2x4z by Molmil](/molmil-images/mine/2x4z) | Crystal Structure of the Human p21-Activated Kinase 4 in Complex with PF-03758309 | Descriptor: | GLYCEROL, PF-3758309, SERINE/THREONINE-PROTEIN KINASE PAK 4 | Authors: | Knighton, D.R, Deng, Y, Murray, B, Guo, C, Piraino, J, Westwick, J, Zhang, C, Lamerdin, J, Dagostino, E, Loi, C.-M, Zager, M, Kraynov, E, Christensen, J, Martinez, R, Kephart, S, Marakovits, J, Karlicek, S, Bergqvist, S, Smeal, T. | Deposit date: | 2010-02-03 | Release date: | 2010-05-19 | Last modified: | 2019-01-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Small-Molecule P21-Activated Kinase Inhibitor Pf- 3758309 is a Potent Inhibitor of Oncogenic Signaling and Tumor Growth. Proc.Natl.Acad.Sci.USA, 107, 2010
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2H7B
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![BU of 2h7b by Molmil](/molmil-images/mine/2h7b) | Solution structure of the eTAFH domain from the human leukemia-associated fusion protein AML1-ETO | Descriptor: | Core-binding factor, ML1-ETO | Authors: | Plevin, M.J, Zhang, J, Guo, C, Roeder, R.G, Ikura, M. | Deposit date: | 2006-06-01 | Release date: | 2006-07-11 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The acute myeloid leukemia fusion protein AML1-ETO targets E proteins via a paired amphipathic helix-like TBP-associated factor homology domain Proc.Natl.Acad.Sci.USA, 103, 2006
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2JOJ
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![BU of 2joj by Molmil](/molmil-images/mine/2joj) | |
8TO0
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![BU of 8to0 by Molmil](/molmil-images/mine/8to0) | 48-nm repeating structure of doublets from mouse sperm flagella | Descriptor: | Cilia- and flagella- associated protein 210, Cilia- and flagella-associated protein 107, Cilia- and flagella-associated protein 141, ... | Authors: | Chen, Z, Shiozak, M, Hass, K.M, Skinner, W, Zhao, S, Guo, C, Polacco, B.J, Yu, Z, Krogan, N.J, Kaake, R.M, Vale, R.D, Agard, D.A. | Deposit date: | 2023-08-02 | Release date: | 2023-11-01 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (7.7 Å) | Cite: | De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking. Cell, 186, 2023
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5YMR
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![BU of 5ymr by Molmil](/molmil-images/mine/5ymr) | The Crystal Structure of IseG | Descriptor: | 2-hydroxyethylsulfonic acid, Formate acetyltransferase, GLYCEROL | Authors: | Lin, L, Zhang, J, Xing, M, Hua, G, Guo, C, Hu, Y, Wei, Y, Ang, E, Zhao, H, Zhang, Y, Yuchi, Z. | Deposit date: | 2017-10-22 | Release date: | 2019-03-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria. Nat Commun, 10, 2019
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7EDK
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![BU of 7edk by Molmil](/molmil-images/mine/7edk) | |
7FJF
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![BU of 7fjf by Molmil](/molmil-images/mine/7fjf) | Cryo-EM structure of a membrane protein(CS) | Descriptor: | CHOLEST-5-EN-3-YL HYDROGEN SULFATE, T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha chain constant, T cell receptor beta variable 6-5,M1-specific T cell receptor beta chain,T cell receptor beta constant 2, ... | Authors: | Chen, Y, Zhu, Y, Gao, W, Zhang, A, Guo, C, Huang, Z. | Deposit date: | 2021-08-03 | Release date: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility. Mol.Cell, 82, 2022
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7FJE
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![BU of 7fje by Molmil](/molmil-images/mine/7fje) | Cryo-EM structure of a membrane protein(LL) | Descriptor: | CHOLESTEROL, T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha chain constant, T cell receptor beta variable 6-5,M1-specific T cell receptor beta chain,T cell receptor beta constant 2, ... | Authors: | Chen, Y, Zhu, Y, Gao, W, Zhang, A, Guo, C, Huang, Z. | Deposit date: | 2021-08-03 | Release date: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility. Mol.Cell, 82, 2022
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7FJD
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![BU of 7fjd by Molmil](/molmil-images/mine/7fjd) | Cryo-EM structure of a membrane protein(WT) | Descriptor: | CHOLESTEROL, T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha chain constant, T cell receptor beta variable 6-5,M1-specific T cell receptor beta chain,T cell receptor beta constant 2, ... | Authors: | Chen, Y, Zhu, Y, Gao, W, Zhang, A, Guo, C, Huang, Z. | Deposit date: | 2021-08-03 | Release date: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility. Mol.Cell, 82, 2022
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