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PDB: 480 件

6J14
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Complex structure of GY-14 and PD-1
分子名称: GY-14 heavy chain V fragment, GY-14 light chain V fragment, Programmed cell death protein 1
著者Chen, D, Tan, S, Whang, H, Zhang, H, Chai, Y, Qi, J, Yan, J, Gao, G.F.
登録日2018-12-27
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The FG Loop of PD-1 Serves as a "Hotspot" for Therapeutic Monoclonal Antibodies in Tumor Immune Checkpoint Therapy.
Iscience, 14, 2019
3GBL
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Crystal structure of grass carp Beta2-microglobulin
分子名称: Beta2-microglobulin
著者Chen, W, Gao, F, Xia, C, Gao, G.F.
登録日2009-02-20
公開日2010-03-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of grass carp Beta2-microglobulin
To be Published
3FN3
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Dimeric Structure of PD-L1
分子名称: Programmed cell death 1 ligand 1
著者Chen, Y, Gao, F, Liu, P, Chu, F, Qi, J, Gao, G.F.
登録日2008-12-23
公開日2009-12-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A dimeric structure of PD-L1: functional units or evolutionary relics?
Protein Cell, 1, 2010
2BCK
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Crystal Structure of HLA-A*2402 Complexed with a telomerase peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Rizkallah, P.J, Jakobsen, B.K, Cole, D.K, Gao, G.F.
登録日2005-10-19
公開日2006-01-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of HLA-A*2402 complexed with a telomerase peptide.
Eur.J.Immunol., 36, 2006
1PV3
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NMR Solution Structure of the Avian FAT-domain of Focal Adhesion Kinase
分子名称: Focal adhesion kinase 1
著者Prutzman, K.C, Gao, G, King, M.L, Iyer, V.V, Mueller, G.A, Schaller, M.D, Campbell, S.L.
登録日2003-06-26
公開日2004-05-25
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The Focal Adhesion Targeting Domain of Focal Adhesion Kinase Contains a Hinge Region that Modulates Tyrosine 926 Phosphorylation.
STRUCTURE, 12, 2004
1J1L
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Crystal structure of human Pirin: a Bcl-3 and Nuclear factor I interacting protein and a cupin superfamily member
分子名称: FE (II) ION, Pirin
著者Pang, H, Bartlam, M, Zeng, Q, Gao, G.F, Rao, Z.
登録日2002-12-10
公開日2003-12-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of human pirin: an iron-binding nuclear protein and transcription cofactor
J.Biol.Chem., 279, 2004
3AL4
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Crystal structure of the swine-origin A (H1N1)-2009 influenza A virus hemagglutinin (HA) reveals similar antigenicity to that of the 1918 pandemic virus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Zhang, W, Qi, J.X, Shi, Y, Li, Q, Yan, J.H, Gao, G.F.
登録日2010-07-22
公開日2010-08-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.872 Å)
主引用文献Crystal structure of the swine-origin A (H1N1)-2009 influenza A virus hemagglutinin (HA) reveals similar antigenicity to that of the 1918 pandemic virus
Protein Cell, 1, 2010
4QY2
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Structure of H10 from human-infecting H10N8 virus in complex with human receptor analog
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid, hemagglutinin
著者Wang, M, Zhang, W, Qi, J, Wang, F, Zhou, J, Bi, Y, Wu, Y, Sun, H, Liu, J, Huang, C, Li, X, Yan, J, Shu, Y, Shi, Y, Gao, G.F.
登録日2014-07-23
公開日2015-01-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.399 Å)
主引用文献Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
4QY1
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Structure of H10 from human-infecting H10N8 in complex with avian receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wang, M, Zhang, W, Qi, J, Wang, F, Zhou, J, Bi, Y, Wu, Y, Sun, H, Liu, J, Huang, C, Li, X, Yan, J, Shu, Y, Shi, Y, Gao, G.F.
登録日2014-07-23
公開日2015-01-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.594 Å)
主引用文献Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
1ZVS
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Crystal structure of the first class MHC mamu and Tat-Tl8 complex
分子名称: Beta-2-microglobulin, MHC class I antigen, Tat-Tl8
著者Lou, Z, Chu, F, Gao, G.F, Rao, Z.
登録日2005-06-02
公開日2006-06-13
最終更新日2019-11-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献First glimpse of the peptide presentation by rhesus macaque MHC class I: crystal structures of Mamu-A*01 complexed with two immunogenic SIV epitopes and insights into CTL escape.
J Immunol., 178, 2007
4R8W
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Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a neutralizing antibody CT149
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of neutralizing antibody CT149, Hemagglutinin, ...
著者Wu, Y, Shi, Y, Qi, J, Gao, G.F.
登録日2014-09-03
公開日2015-08-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.795 Å)
主引用文献A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus
Nat Commun, 6, 2015
8KA8
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Cryo-EM structure of SARS-CoV-2 Delta RBD in complex with golden hamster ACE2 (local refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ...
著者Niu, S, Zhao, Z.N, Chai, Y, Gao, G.F.
登録日2023-08-02
公開日2024-01-31
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.96 Å)
主引用文献Structural basis and analysis of hamster ACE2 binding to different SARS-CoV-2 spike RBDs.
J.Virol., 98, 2024
8KC2
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Cryo-EM structure of SARS-CoV-2 BA.3 RBD in complex with golden hamster ACE2 (local refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ...
著者Niu, S, Zhao, Z.N, Chai, Y, Gao, G.F.
登録日2023-08-05
公開日2024-01-31
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis and analysis of hamster ACE2 binding to different SARS-CoV-2 spike RBDs.
J.Virol., 98, 2024
6IEX
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Crystal structure of HLA-B*4001 in complex with SARS-CoV derived peptide N216-225 GETALALLLL
分子名称: Beta-2-microglobulin, GLY-GLU-THR-ALA-LEU-ALA-LEU-LEU-LEU-LEU, MHC class I antigen
著者Ji, W, Niu, L, Peng, W, Zhang, Y, Shi, Y, Qi, J, Gao, G.F, Liu, W.J.
登録日2018-09-17
公開日2019-09-18
最終更新日2021-03-31
実験手法X-RAY DIFFRACTION (2.314 Å)
主引用文献Salt bridge-forming residues positioned over viral peptides presented by MHC class I impacts T-cell recognition in a binding-dependent manner.
Mol.Immunol., 112, 2019
2VLE
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The structure of daidzin, a naturally occurring anti alcohol- addiction agent, in complex with human mitochondrial aldehyde dehydrogenase
分子名称: ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL, DAIDZIN
著者Lowe, E.D, Gao, G.Y, Johnson, L.N, Keung, W.M.
登録日2008-01-13
公開日2008-08-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of Daidzin, a Naturally Occurring Anti-Alcohol-Addiction Agent, in Complex with Human Mitochondrial Aldehyde Dehydrogenase.
J.Med.Chem., 51, 2008
6U3Q
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The atomic structure of a human adeno-associated virus capsid isolate (AAVhu69/AAVv66)
分子名称: Capsid protein VP1
著者Hsu, H.-L, Brown, A, Loveland, A, Tai, P, Korostelev, A, Gao, G.
登録日2019-08-22
公開日2020-05-27
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.46 Å)
主引用文献Structural characterization of a novel human adeno-associated virus capsid with neurotropic properties.
Nat Commun, 11, 2020
2HP4
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Computational design and crystal structure of an enhanced affinity mutant human CD8-alpha-alpha co-receptor
分子名称: GLYCEROL, SULFATE ION, T-cell surface glycoprotein CD8 alpha chain
著者Rizkallah, P.J, Cole, D.K, Jakobsen, B.K, Boulter, J.M, Glick, M, Gao, G.F.
登録日2006-07-17
公開日2007-02-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Computational design and crystal structure of an enhanced affinity mutant human CD8 alphaalpha coreceptor
Proteins, 67, 2007
6J2E
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Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with Ebola virus-derived peptide EBOV-NP1
分子名称: Beta-2-microglobulin, EBOV-NP1, MHC class I antigen
著者Lu, D, Liu, K.F, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, G.F, Liu, W.J.
登録日2019-01-01
公開日2019-09-18
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats.
Plos Biol., 17, 2019
6J2G
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Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with Ebola virus-derived peptide EBOV-NP2
分子名称: Beta-2-microglobulin, EBOV-NP2, Ptal-N*01:01
著者Lu, D, Liu, K.F, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, G.F, Liu, W.J.
登録日2019-01-01
公開日2019-09-18
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats.
Plos Biol., 17, 2019
6J2H
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Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 mutant (Met52 Asp53 Leu54 deleted) in complex with Hendra virus-derived peptide HeV1
分子名称: Beta-2-microglobulin, HeV1, Ptal-N*01:01 (Met52 Asp53 Leu54 deleted)
著者Lu, D, Liu, K.F, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, G.F, Liu, W.J.
登録日2019-01-01
公開日2019-09-18
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats.
Plos Biol., 17, 2019
6J2F
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Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with Hendra virus-derived peptide HeV2
分子名称: HeV2, Ptal-N*01:01, beta-2 microglobulin
著者Lu, D, Liu, K.F, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, G.F, Liu, W.J.
登録日2019-01-01
公開日2019-09-18
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats.
Plos Biol., 17, 2019
6J2I
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Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with H17N10 influenza-like virus-derivrd peptide H17N10-NP
分子名称: Beta-2-microglobulin, H17N10-NP, Ptal-N*01:01
著者Lu, D, Liu, K.F, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, G.F, Liu, W.J.
登録日2019-01-01
公開日2019-09-18
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats.
Plos Biol., 17, 2019
6J2J
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Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with MERS-CoV-derived peptide MERS-CoV-S3
分子名称: Beta-2-microglobulin, MERS-CoV-S3, Ptal-N*01:01
著者Lu, D, Liu, K.F, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, G.F, Liu, W.J.
登録日2019-01-01
公開日2019-09-18
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats.
Plos Biol., 17, 2019
3NCW
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Crystal structure of EHEC O157:H7 intimin
分子名称: Intimin adherence protein
著者Yi, Y, Gao, F, Gao, G.F, Zou, Q.M.
登録日2010-06-06
公開日2011-01-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of EHEC Intimin: Insights into the Complementarity between EPEC and EHEC
Plos One, 5, 2010
6J1W
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The structure of HLA-A*3001/RT313
分子名称: ALA-ILE-PHE-GLN-SER-SER-MET-THR-LYS, Beta-2-microglobulin, HLA-A*3001
著者Zhu, S.Y, Liu, K.F, Chai, Y, Ding, C.M, Lv, J.X, Gao, G.F, Lou, Y.L, Liu, W.J.
登録日2018-12-29
公開日2019-09-25
実験手法X-RAY DIFFRACTION (1.501 Å)
主引用文献Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides.
Front Immunol, 10, 2019

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