2VLE
The structure of daidzin, a naturally occurring anti alcohol- addiction agent, in complex with human mitochondrial aldehyde dehydrogenase
Replaces: 1OF7Summary for 2VLE
Entry DOI | 10.2210/pdb2vle/pdb |
Related | 1CW3 1NZW 1NZX 1NZZ 1O00 1O01 1O02 1O04 1O05 1ZUM |
Descriptor | ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL, DAIDZIN (3 entities in total) |
Functional Keywords | transit peptide, aldehyde dehydrogenase, nad, daidzin, acetylation, polymorphism, mitochondrion, alcohol abuse, oxidoreductase |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Mitochondrion matrix: P05091 |
Total number of polymer chains | 8 |
Total formula weight | 435091.74 |
Authors | Lowe, E.D.,Gao, G.Y.,Johnson, L.N.,Keung, W.M. (deposition date: 2008-01-13, release date: 2008-08-19, Last modification date: 2023-12-13) |
Primary citation | Lowe, E.D.,Gao, G.Y.,Johnson, L.N.,Keung, W.M. Structure of Daidzin, a Naturally Occurring Anti-Alcohol-Addiction Agent, in Complex with Human Mitochondrial Aldehyde Dehydrogenase. J.Med.Chem., 51:4482-, 2008 Cited by PubMed: 18613661DOI: 10.1021/JM800488J PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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