Dimeric Structure of PD-L1

Summary for 3FN3

DescriptorProgrammed cell death 1 ligand 1 (1 entity in total)
Functional Keywordsb7-h1, pd-l1, programmed cell death 1, cell membrane, glycoprotein, immunoglobulin domain, membrane, receptor, transmembrane, immune system
Biological sourceHomo sapiens (human)
Cellular locationIsoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Endomembrane system; Single-pass type I membrane protein Q9NZQ7
Total number of polymer chains2
Total molecular weight50711.59
Chen, Y.,Gao, F.,Liu, P.,Chu, F.,Qi, J.,Gao, G.F. (deposition date: 2008-12-23, release date: 2009-12-29, Last modification date: 2011-07-13)
Primary citation
Chen, Y.,Liu, P.,Gao, F.,Cheng, H.,Qi, J.,Gao, G.F.
A dimeric structure of PD-L1: functional units or evolutionary relics?
Protein Cell, 1:153-160, 2010
PubMed: 21203985 (PDB entries with the same primary citation)
DOI: 10.1007/s13238-010-0022-1
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.290182.1%12.7%1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3fn3
no rotation
Molmil generated image of 3fn3
rotated about x axis by 90°
Molmil generated image of 3fn3
rotated about y axis by 90°