6BR6

N2 neuraminidase in complex with a novel antiviral compound

Summary for 6BR6

• Entry DOI: 10.2210/pdb6br6/pdb
• Related: 6BR5
• Descriptor: Neuraminidase, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: complex, hydrolase
• Biological source: Influenza A virus (A/Perth/16/2009(H3N2))
• Total number of polymer chains: 1
• Total formula weight: 44607.19

Authors

Li, L.H.,Ve, T.,Pascolutti, M.,Hadhazi, A.,Bailly, B.,Thomson, R.J.,Gao, G.F.,von Itzstein, M. (deposition date: 2017-11-30, release date: 2018-03-07, Last modification date: 2020-07-29)

• Primary citation: Hadhazi, A.,Li, L.,Bailly, B.,Maggioni, A.,Martin, G.,Dirr, L.,Dyason, J.C.,Thomson, R.J.,Gao, G.F.,Borbas, A.,Ve, T.,Pascolutti, M.,von Itzstein, M.; A Sulfonozanamivir Analogue Has Potent Anti-influenza Virus Activity.; ChemMedChem, 13:785-789, 2018; PubMed: 29453852; DOI: 10.1002/cmdc.201800092

Experimental method

X-RAY DIFFRACTION (2.03983884352 Å)