8X81

Structure of leptin-LepR trimer with a large gap

This is a non-PDB format compatible entry.

Summary for 8X81

• Entry DOI: 10.2210/pdb8x81/pdb
• EMDB information: 38132
• Descriptor: Leptin receptor, Leptin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: cytokine receptor, hexamer, cytokine
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 345543.70

Authors

Xie, Y.F.,Gao, G.F. (deposition date: 2023-11-27, release date: 2024-08-07, Last modification date: 2024-10-23)

• Primary citation: Xie, Y.F.,Li, X.,Qi, J.,Shang, G.,Lu, D.,Gao, G.F.; Structural plasticity of human leptin binding to its receptor LepR; Hlife, 1:115-123, 2023; DOI: 10.1016/j.hlife.2023.10.010

Experimental method

ELECTRON MICROSCOPY (3.77 Å)