3I6K

Newly identified epitope from SARS-CoV membrane protein complexed with HLA-A*0201

Summary for 3I6K
DescriptorHLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Membrane glycoprotein peptide, ... (4 entities in total)
Functional Keywordshla-a2, sars-cov, membrane glycoprotein, disulfide bond, glycoprotein, host-virus interaction, immune response, membrane, mhc i, phosphoprotein, transmembrane, disease mutation, glycation, immunoglobulin domain, pyrrolidone carboxylic acid, secreted, envelope protein, golgi apparatus, viral matrix protein, virion, immune system
Biological sourceHomo sapiens (human)
More
Cellular locationMembrane; Single-pass type I membrane protein: P01892
Secreted: P61769
Total number of polymer chains6
Total formula weight89481.61
Authors
Liu, J.,Sun, Y.,Qi, J.,Chu, F.,Wu, H.,Gao, F.,Li, T.,Yan, J.,Gao, G.F. (deposition date: 2009-07-07, release date: 2010-06-16, Last modification date: 2011-07-13)
Primary citationChu, F.,Gao, F.,Gao, G.F.,Li, T.,Liu, J.,Qi, J.,Sun, Y.,Wu, H.,Yan, J.
The membrane protein of severe acute respiratory syndrome coronavirus acts as a dominant immunogen revealed by a clustering region of novel functionally and structurally defined cytotoxic T-lymphocyte epitopes
J Infect Dis, 202:1171-1180, 2010
PubMed: 20831383
DOI: 110.1086/656315
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation
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PDB entries from 2021-06-23