3I6K

Newly identified epitope from SARS-CoV membrane protein complexed with HLA-A*0201

Summary for 3I6K

DescriptorHLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Membrane glycoprotein peptide, ... (4 entities in total)
Functional Keywordshla-a2, sars-cov, membrane glycoprotein, disulfide bond, glycoprotein, host-virus interaction, immune response, membrane, mhc i, phosphoprotein, transmembrane, disease mutation, glycation, immunoglobulin domain, pyrrolidone carboxylic acid, secreted, envelope protein, golgi apparatus, viral matrix protein, virion, immune system
Biological sourceHomo sapiens (human)
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Cellular locationMembrane; Single-pass type I membrane protein P01892
Secreted P61769
Total number of polymer chains6
Total molecular weight89481.61
Authors
Liu, J.,Sun, Y.,Qi, J.,Chu, F.,Wu, H.,Gao, F.,Li, T.,Yan, J.,Gao, G.F. (deposition date: 2009-07-07, release date: 2010-06-16, Last modification date: 2011-07-13)
Primary citation
Liu, J.,Sun, Y.,Qi, J.,Chu, F.,Wu, H.,Gao, F.,Li, T.,Yan, J.,Gao, G.F.
The membrane protein of severe acute respiratory syndrome coronavirus acts as a dominant immunogen revealed by a clustering region of novel functionally and structurally defined cytotoxic T-lymphocyte epitopes
J Infect Dis, 202:1171-1180, 2010
PubMed: 20831383 (PDB entries with the same primary citation)
DOI: 10.1086/656315
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2391004.2%2.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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More Biological unit images

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Molmil generated image of 3i6k
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Molmil generated image of 3i6k
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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (3i6k.pdb2.gz [68.43 KB])
Coordinate files for Biological unit (3i6k.pdb1.gz [67.16 KB])