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PDB: 350 件

2HNQ
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CRYSTAL STRUCTURE OF HUMAN PROTEIN TYROSINE PHOSPHATASE 1B
分子名称: PROTEIN-TYROSINE PHOSPHATASE-1B, TUNGSTATE(VI)ION
著者Barford, D, Flint, A.J, Tonks, N.K.
登録日1994-09-28
公開日1994-12-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal structure of human protein tyrosine phosphatase 1B.
Science, 263, 1994
2HNP
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CRYSTAL STRUCTURE OF HUMAN PROTEIN TYROSINE PHOSPHATASE 1B
分子名称: PROTEIN-TYROSINE PHOSPHATASE-1B
著者Barford, D, Flint, A.J, Tonks, N.K.
登録日1994-09-19
公開日1994-12-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal structure of human protein tyrosine phosphatase 1B.
Science, 263, 1994
3ZV2
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Human protein-tyrosine phosphatase 1b C215A, S216A mutant
分子名称: Tyrosine-protein phosphatase non-receptor type 1
著者Barford, D, Salmeen, A, Tonks, N.K.
登録日2011-07-22
公開日2011-08-31
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Conformation-sensing antibodies stabilize the oxidized form of PTP1B and inhibit its phosphatase activity.
Cell, 147, 2011
2Y6T
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Molecular Recognition of Chymotrypsin by the Serine Protease Inhibitor Ecotin from Yersinia pestis
分子名称: CHYMOTRYPSINOGEN A, ECOTIN, SULFATE ION
著者Clark, E.A, Walker, N, Ford, D.C, Cooper, I.A, Oyston, P.C.F, Acharya, K.R.
登録日2011-01-26
公開日2011-04-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Molecular Recognition of Chymotrypsin by the Serine Protease Inhibitor Ecotin from Yersinia Pestis.
J.Biol.Chem., 286, 2011
2W3L
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Crystal Structure of Chimaeric Bcl2-xL and Phenyl Tetrahydroisoquinoline Amide Complex
分子名称: 1-(2-{[(3S)-3-(aminomethyl)-3,4-dihydroisoquinolin-2(1H)-yl]carbonyl}phenyl)-4-chloro-5-methyl-N,N-diphenyl-1H-pyrazole-3-carboxamide, APOPTOSIS REGULATOR BCL-2
著者Porter, J, Payne, A, de Candole, B, Ford, D, Hutchinson, B, Trevitt, G, Turner, J, Edwards, C, Watkins, C, Whitcombe, I, Davis, J, Stubberfield, C, Fisher, M, Lamers, M.
登録日2008-11-13
公開日2008-12-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Tetrahydroisoquinoline Amide Substituted Phenyl Pyrazoles as Selective Bcl-2 Inhibitors.
Bioorg.Med.Chem.Lett., 19, 2009
7R5R
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Structure of the human CCAN CENP-A alpha-satellite complex
分子名称: Centromere protein C, DNA (171-MER), Histone H2A type 1-C, ...
著者Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D.
登録日2022-02-11
公開日2022-04-27
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.44 Å)
主引用文献Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Science, 376, 2022
8QV0
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Structure of the native microtubule lattice nucleated from the yeast spindle pole body
分子名称: Tubulin alpha-1 chain, Tubulin beta chain
著者Dendooven, T, Yatskevich, S, Burt, A, Bellini, D, Kilmartin, J, Barford, D.
登録日2023-10-17
公開日2024-04-24
最終更新日2024-07-31
実験手法ELECTRON MICROSCOPY (6.6 Å)
主引用文献Structure of the native gamma-tubulin ring complex capping spindle microtubules.
Nat.Struct.Mol.Biol., 31, 2024
8QV3
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Structure of the y-Tubulin Small Complex (yTuSC) as part of the native y-Tubulin Ring Complex (yTuRC) capping microtubule minus ends at the spindle pole body
分子名称: GUANOSINE-5'-TRIPHOSPHATE, Spindle pole body component, Spindle pole body component 110, ...
著者Dendooven, T, Yatskevich, S, Burt, A, Bellini, D, Kilmartin, J, Barford, D.
登録日2023-10-17
公開日2024-04-24
最終更新日2024-07-31
実験手法ELECTRON MICROSCOPY (8.2 Å)
主引用文献Structure of the native gamma-tubulin ring complex capping spindle microtubules.
Nat.Struct.Mol.Biol., 31, 2024
8QV2
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Structure of the native y-Tubulin Ring Complex (yTuRC) capping microtubule minus ends at the spindle pole body
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Spindle pole body component, ...
著者Dendooven, T, Yatskevich, S, Burt, A, Bellini, D, Kilmartin, J, Barford, D.
登録日2023-10-17
公開日2024-04-24
最終更新日2024-07-31
実験手法ELECTRON MICROSCOPY (9.2 Å)
主引用文献Structure of the native gamma-tubulin ring complex capping spindle microtubules.
Nat.Struct.Mol.Biol., 31, 2024
7R5S
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Structure of the human CCAN bound to alpha satellite DNA
分子名称: Centromere protein H, Centromere protein I, Centromere protein K, ...
著者Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D.
登録日2022-02-11
公開日2022-04-27
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Science, 376, 2022
7R5V
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Structure of the human CCAN CENP-A alpha-satellite complex
分子名称: Centromere protein H, Centromere protein I, Centromere protein K, ...
著者Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D.
登録日2022-02-11
公開日2022-04-27
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.55 Å)
主引用文献Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Science, 376, 2022
8QRY
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Crystal structure of the yeast spindle body component Spc98
分子名称: Spindle pole body component
著者Bellini, D, Yatskevich, S, Barford, D.
登録日2023-10-09
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Crystal structure of the yeast spindle body component Spc98
To Be Published
1UVJ
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The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 7nt RNA
分子名称: 5'-R(*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase
著者Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M.
登録日2004-01-21
公開日2004-02-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase.
Structure, 12, 2004
1UVK
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The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 dead-end complex
分子名称: GUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M.
登録日2004-01-21
公開日2004-02-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase.
Structure, 12, 2004
6TGC
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BU of 6tgc by Molmil
CryoEM structure of the ternary DOCK2-ELMO1-RAC1 complex.
分子名称: Dedicator of cytokinesis protein 2, Engulfment and cell motility protein 1, Ras-related C3 botulinum toxin substrate 1
著者Chang, L, Yang, J, Chang, J.H, Zhang, Z, Boland, A, McLaughlin, S.H, Abu-Thuraia, A, Killoran, R.C, Smith, M.J, Cote, J.F, Barford, D.
登録日2019-11-15
公開日2020-07-29
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state.
Nat Commun, 11, 2020
6TLJ
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Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 3.8 angstrom resolution
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Alfieri, C, Barford, D.
登録日2019-12-02
公開日2020-02-19
最終更新日2020-06-17
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献A unique binding mode of Nek2A to the APC/C allows its ubiquitination during prometaphase.
Embo Rep., 21, 2020
8S4G
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BU of 8s4g by Molmil
Cryo-EM structure of the Anaphase-promoting complex/cyclosome (APC/C) bound to co-activator Cdh1 at 3.2 Angstrom resolution
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Hoefler, A, Yu, J, Chang, L, Zhang, Z, Yang, J, Boland, A, Barford, D.
登録日2024-02-21
公開日2024-03-13
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献New structural features of the APC/C revealed by high resolution cryo-EM structures of apo-APC/C and the APC/C-CDH1-EMI1 complex
To Be Published
1G1H
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CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH A BIS-PHOSPHORYLATED PEPTIDE (ETD(PTR)(PTR)RKGGKGLL) FROM THE INSULIN RECEPTOR KINASE
分子名称: BI-PHOSPHORYLATED PEPTIDE FROM THE INSULIN RECEPTOR KINASE, PROTEIN TYROSINE PHOSPHATASE 1B
著者Salmeen, A, Andersen, J.N, Myers, M.P, Tonks, N.K, Barford, D.
登録日2000-10-11
公開日2001-01-17
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B.
Mol.Cell, 6, 2000
1G1G
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CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH A MONO-PHOSPHORYLATED PEPTIDE (ETDY(PTR)RKGGKGLL) FROM THE INSULIN RECEPTOR KINASE
分子名称: MONO-PHOSPHORYLATED PEPTIDE FROM THE INSULIN RECEPTOR KINASE, PROTEIN TYROSINE PHOSPHATASE 1B
著者Salmeen, A, Andersen, J.N, Myers, M.P, Tonks, N.K, Barford, D.
登録日2000-10-11
公開日2001-01-17
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B.
Mol.Cell, 6, 2000
1G1F
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CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH A TRI-PHOSPHORYLATED PEPTIDE (RDI(PTR)ETD(PTR)(PTR)RK) FROM THE INSULIN RECEPTOR KINASE
分子名称: PROTEIN TYROSINE PHOSPHATASE 1B, TRI-PHOSPHORYLATED PEPTIDE FROM THE INSULIN RECEPTOR KINASE
著者Salmeen, A, Andersen, J.N, Myers, M.P, Tonks, N.K, Barford, D.
登録日2000-10-11
公開日2001-01-17
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B.
Mol.Cell, 6, 2000
5A98
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Crystal structure of Trichoplusia ni CPV15 polyhedra
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, POLYHEDRIN
著者Ji, X, Axford, D, Owen, R, Evans, G, Ginn, H.M, Sutton, G, Stuart, D.I.
登録日2015-07-17
公開日2015-09-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.816 Å)
主引用文献Polyhedra Structures and the Evolution of the Insect Viruses.
J.Struct.Biol., 192, 2015
5A99
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Crystal structure of Operophtera brumata CPV19 polyhedra
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, POLYHEDRIN
著者Ji, X, Axford, D, Owen, R, Evans, G, Ginn, H.M, Sutton, G, Stuart, D.I.
登録日2015-07-17
公開日2015-09-02
最終更新日2015-10-14
実験手法X-RAY DIFFRACTION (1.511 Å)
主引用文献Polyhedra Structures and the Evolution of the Insect Viruses.
J.Struct.Biol., 192, 2015
5A9P
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Crystal structure of Operophtera brumata CPV18 polyhedra
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, POLYHEDRIN
著者Ji, X, Axford, D, Owen, R, Evans, G, Ginn, H.M, Sutton, G, Stuart, D.I.
登録日2015-07-21
公開日2015-09-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.476 Å)
主引用文献Polyhedra Structures and the Evolution of the Insect Viruses.
J.Struct.Biol., 192, 2015
6TM5
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Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Nek2A substrate at 3.9 angstrom resolution
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Alfieri, C, Barford, D.
登録日2019-12-03
公開日2020-02-19
最終更新日2020-06-17
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献A unique binding mode of Nek2A to the APC/C allows its ubiquitination during prometaphase.
Embo Rep., 21, 2020
5A96
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Crystal structure of Lymantria dispar CPV14 polyhedra
分子名称: GUANOSINE-5'-TRIPHOSPHATE, POLYHEDRIN
著者Ji, X, Axford, D, Owen, R, Evans, G, Ginn, H.M, Sutton, G, Stuart, D.I.
登録日2015-07-17
公開日2015-09-02
最終更新日2015-10-14
実験手法X-RAY DIFFRACTION (1.914 Å)
主引用文献Polyhedra Structures and the Evolution of the Insect Viruses.
J.Struct.Biol., 192, 2015

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