7R5S

Structure of the human CCAN bound to alpha satellite DNA

Summary for 7R5S

Entry DOI	10.2210/pdb7r5s/pdb
EMDB information	14336
Descriptor	Centromere protein H, Centromere protein Q, Centromere protein U, ... (18 entities in total)
Functional Keywords	chromosome, kinetochore, cell division, centromere, cell cycle
Biological source	Homo sapiens (human) More
Total number of polymer chains	17
Total formula weight	539113.46
Authors	Yatskevich, S.,Muir, K.W.,Bellini, D.,Zhang, Z.,Yang, J.,Tischer, T.,Predin, M.,Dendooven, T.,McLaughlin, S.H.,Barford, D. (deposition date: 2022-02-11, release date: 2022-04-27, Last modification date: 2022-06-01)
Primary citation	Yatskevich, S.,Muir, K.W.,Bellini, D.,Zhang, Z.,Yang, J.,Tischer, T.,Predin, M.,Dendooven, T.,McLaughlin, S.H.,Barford, D. Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome. Science, 376:844-852, 2022 Cited by PubMed: 35420891 DOI: 10.1126/science.abn3810 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.83 Å)

Structure validation