6TKY
 
 | | Crystal structure of the DHR2 domain of DOCK10 in complex with CDC42 | | 分子名称: | Cell division control protein 42 homolog, Dedicator of cytokinesis protein 10, GLYCEROL | | 著者 | Barford, D, Fan, D, Cronin, N, Yang, J. | | 登録日 | 2019-11-29 | | 公開日 | 2020-01-22 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structural basis for CDC42 and RAC activation by the dual specificity GEF DOCK10
Biorxiv, 2022
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6TKZ
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6TM1
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8GPB
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9GPB
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4YCR
 | | Structure determination of an integral membrane protein at room temperature from crystals in situ | | 分子名称: | Tellurite resistance protein TehA homolog, octyl beta-D-glucopyranoside | | 著者 | Axford, D, Hu, N.J, Foadi, J, Choudhury, H.G, Iwata, S, Beis, K, Evans, G, Alguel, Y. | | 登録日 | 2015-02-20 | | 公開日 | 2015-06-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure determination of an integral membrane protein at room temperature from crystals in situ.
Acta Crystallogr.,Sect.D, 71, 2015
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7GPB
 | | STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP | | 分子名称: | ADENOSINE MONOPHOSPHATE, GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Barford, D, Hu, S.-H, Johnson, L.N. | | 登録日 | 1990-11-13 | | 公開日 | 1992-10-15 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP.
J.Mol.Biol., 218, 1991
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5M3S
 | | Low-dose fixed target serial synchrotron crystallography structure of Metmyoglobin | | 分子名称: | Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | | 著者 | Axford, D, Owen, R.L, Sherrell, D, Muller-Werkmeister, H. | | 登録日 | 2016-10-17 | | 公開日 | 2016-12-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Low-dose fixed-target serial synchrotron crystallography.
Acta Crystallogr D Struct Biol, 73, 2017
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5O8N
 | | Structure of thermolysin at room temperature via a method of acoustically induced rotation. | | 分子名称: | CALCIUM ION, CHLORIDE ION, SODIUM ION, ... | | 著者 | Axford, D.N, Burton, C, Docker, P, Prince, M, Topham, P.D. | | 登録日 | 2017-06-13 | | 公開日 | 2017-08-09 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | An acoustic on-chip goniometer for room temperature macromolecular crystallography.
Lab Chip, 17, 2017
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8A5Y
 | | S. cerevisiae apo unphosphorylated APC/C. | | 分子名称: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ... | | 著者 | Barford, D, Fernandez-Vazquez, E, Zhang, Z, Yang, J. | | 登録日 | 2022-06-16 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | Cryo-EM structure of the S. cerevisiae APC/C-Cdh1 complex and comparison to apo unphosphorylated and phosphorylated states
To Be Published
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8A61
 | | S. cerevisiae apo phosphorylated APC/C | | 分子名称: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ... | | 著者 | Barford, D, Fernandez-Vazquez, E, Zhang, Z, Yang, J. | | 登録日 | 2022-06-16 | | 公開日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (5.4 Å) | | 主引用文献 | Cryo-EM structure of the S. cerevisiae apo phosphorylated APC/C
To Be Published
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8A3T
 | | S. cerevisiae APC/C-Cdh1 complex | | 分子名称: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ... | | 著者 | Barford, D, Vazquez-Fernandez, E, Zhang, Z, Yang, J. | | 登録日 | 2022-06-09 | | 公開日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structure of the S. cerevisiae APC/C-Cdh1 complex
To Be Published
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6QQ3
 | | The room temperature structure of lysozyme via the acoustic levitation of a droplet | | 分子名称: | ACETATE ION, CHLORIDE ION, Lysozyme C, ... | | 著者 | Axford, D.N, Docker, P, Dye, E, Morris, R. | | 登録日 | 2019-02-17 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Non-Contact Universal Sample Presentation for Room Temperature Macromolecular Crystallography Using Acoustic Levitation.
Sci Rep, 9, 2019
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3KAE
 | | Cdc27 N-terminus | | 分子名称: | CHLORIDE ION, GLYCEROL, Possible protein of nuclear scaffold, ... | | 著者 | Barford, D, Zhang, Z, Roe, S.M. | | 登録日 | 2009-10-19 | | 公開日 | 2010-03-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.298 Å) | | 主引用文献 | Molecular structure of the N-terminal domain of the APC/C subunit Cdc27 reveals a homo-dimeric tetratricopeptide repeat architecture
J.Mol.Biol., 397, 2010
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1GPA
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1WAO
 | | PP5 structure | | 分子名称: | MANGANESE (II) ION, SERINE/THREONINE PROTEIN PHOSPHATASE 5 | | 著者 | Barford, D. | | 登録日 | 2004-10-27 | | 公開日 | 2005-02-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Molecular Basis for Tpr Domain-Mediated Regulation of Protein Phosphatase 5
Embo J., 24, 2005
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1UWH
 | | The complex of wild type B-RAF and BAY439006. | | 分子名称: | 4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE, B-RAF PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE, CHLORIDE ION | | 著者 | Barford, D, Roe, S.M, Wan, P.T.C, Cancer Genome Project | | 登録日 | 2004-02-05 | | 公開日 | 2004-03-19 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Mechanism of Activation of the Raf-Erk Signaling Pathway by Oncogenic Mutations of B-Raf
Cell(Cambridge,Mass.), 116, 2004
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1UWJ
 | | The complex of mutant V599E B-RAF and BAY439006. | | 分子名称: | 4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE, B-RAF PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE | | 著者 | Barford, D, Roe, S.M, Wan, P.T.C, Cancer Genome Project | | 登録日 | 2004-02-05 | | 公開日 | 2004-03-19 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Mechanism of Activation of the Raf-Erk Signaling Pathway by Oncogenic Mutations of B-Raf
Cell(Cambridge,Mass.), 116, 2004
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1PTU
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1GZK
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1PTT
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1PTV
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1GZN
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1GZO
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6TNT
 | | SUMOylated apoAPC/C with repositioned APC2 WHB domain | | 分子名称: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | | 著者 | Barford, D, Yatskevich, S. | | 登録日 | 2019-12-10 | | 公開日 | 2021-01-13 | | 最終更新日 | 2021-07-28 | | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | | 主引用文献 | Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation.
Cell Rep, 34, 2021
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