6TM1

Crystal structure of the DHR2 domain of DOCK10 in complex with RAC3

Summary for 6TM1

Entry DOI	10.2210/pdb6tm1/pdb
Descriptor	Dedicator of cytokinesis protein 10, Ras-related C3 botulinum toxin substrate 3 (3 entities in total)
Functional Keywords	dock10 gef rac3 gtpase, signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	127515.74
Authors	Barford, D.,Fan, D.,Cronin, N.,Yang, J. (deposition date: 2019-12-03, release date: 2020-01-22, Last modification date: 2024-01-24)
Primary citation	Fan, D.,Yang, J.,Cronin, N.,Barford, D. Structural basis for CDC42 and RAC activation by the dual specificity GEF DOCK10 Biorxiv, 2022 Cited by DOI: 10.1101/2022.06.15.496229 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.71 Å)

Structure validation