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PDB: 31 件

4RL2
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Structural and mechanistic insights into NDM-1 catalyzed hydrolysis of cephalosporins
分子名称: (1R)-2-({(R)-carboxy[(2R,5S)-4-carboxy-5-methyl-5,6-dihydro-2H-1,3-thiazin-2-yl]methyl}amino)-2-oxo-1-phenylethanaminium, Beta-lactamase NDM-1, ZINC ION
著者Feng, H, Ding, J, Zhu, D, Liu, X, Xu, X, Zhang, Y, Zang, S, Wang, D.-C, Liu, W.
登録日2014-10-15
公開日2014-11-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.008 Å)
主引用文献Structural and Mechanistic Insights into NDM-1 Catalyzed Hydrolysis of Cephalosporins.
J.Am.Chem.Soc., 136, 2014
4RM5
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Structural and mechanistic insights into NDM-1 catalyzed hydrolysis of cephalosporins
分子名称: Beta-lactamase NDM-1, ZINC ION
著者Feng, H, Ding, J, Zhu, D, Liu, X, Xu, X, Zhang, Y, Zang, S, Wang, D.-C, Liu, W.
登録日2014-10-19
公開日2014-11-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and Mechanistic Insights into NDM-1 Catalyzed Hydrolysis of Cephalosporins.
J.Am.Chem.Soc., 136, 2014
4RL0
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Structural and mechanistic insights into NDM-1 catalyzed hydrolysis of cephalosporins
分子名称: (2R,5S)-5-[(carbamoyloxy)methyl]-2-[(R)-carboxy{[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino}methyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Beta-lactamase NDM-1, ZINC ION
著者Feng, H, Ding, J, Zhu, D, Liu, X, Xu, X, Zhang, Y, Zang, S, Wang, D.-C, Liu, W.
登録日2014-10-14
公開日2014-11-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural and Mechanistic Insights into NDM-1 Catalyzed Hydrolysis of Cephalosporins.
J.Am.Chem.Soc., 136, 2014
1YYX
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The solution structure of a redesigned apocytochrome B562 (Rd-apocyt b562) at 2.8M urea
分子名称: Redesigned apo-cytochrome b562
著者Feng, H, Vu, N, Bai, Y, Berkeley Structural Genomics Center (BSGC)
登録日2005-02-25
公開日2005-08-25
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Detection and structure determination of an equilibrium unfolding intermediates of Rd-apocytochrome b562: native fold with non-native hydrophobic interactions
J.Mol.Biol., 343, 2004
1YZA
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The solution structure of a redesigned apocytochrome B562 (Rd-apocyt b562) with the N-terminal helix unfolded
分子名称: Redesigned apo-cytochrome b562
著者Feng, H, Takei, T, Lipsitz, R, Tjandra, N, Bai, Y, Berkeley Structural Genomics Center (BSGC)
登録日2005-02-28
公開日2005-08-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Specific non-native hydrophobic interactions in a hidden folding intermediate: implication for protein folding
Biochemistry, 42, 2003
1YYJ
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The NMR solution structure of a redesigned apocytochrome b562:Rd-apocyt b562
分子名称: redesigned apocytochrome B562
著者Feng, H, Takei, J, Lipsitz, R, Tjandra, N, Bai, Y, Berkeley Structural Genomics Center (BSGC)
登録日2005-02-25
公開日2005-08-25
最終更新日2023-09-27
実験手法SOLUTION NMR
主引用文献Specific non-native hydrophobic interactions in a hidden folding intermediate: implications for protein folding
Biochemistry, 42, 2003
1YZC
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The solution structure of a redesigned apocytochrome B562 (Rd-apocyt b562) with the N- and a part of the C-terminal helices unfolded
分子名称: edesigned apo-cytochrome b562
著者Feng, H, Zhou, Z, Bai, Y, Berkeley Structural Genomics Center (BSGC)
登録日2005-02-28
公開日2006-03-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A protein folding pathway with multiple folding intermediates at atomic resolution
Proc.Natl.Acad.Sci.Usa, 102, 2005
5HDK
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Crystal structure of heat shock factor 2-DBD
分子名称: CHLORIDE ION, Heat shock factor protein 2, POTASSIUM ION, ...
著者Feng, H, Liu, W, Wang, D.C.
登録日2016-01-05
公開日2017-01-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献HSF1-DBD crystal structure
To Be Published
5HDN
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Crystal structure of heat shock factor1-DBD complex with ds-DNA and TtT
分子名称: CITRIC ACID, DNA (5'-D(*GP*GP*TP*TP*CP*TP*AP*GP*AP*AP*CP*C)-3'), Heat shock factor protein 1, ...
著者Feng, H, Liu, W, Wang, D.C.
登録日2016-01-05
公開日2017-01-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献HSF1-DBD crystal structure
To Be Published
5HDG
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crystal structure of heat shock factor 1-DBD
分子名称: Heat shock factor protein 1, SODIUM ION
著者Feng, H, Liu, W, Wang, D.C.
登録日2016-01-05
公開日2017-01-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献HSF1-DBD crystal structure
To Be Published
5YPI
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Crystal structure of NDM-1 bound to hydrolyzed imipenem representing an EI1 complex
分子名称: (2R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-(2-methanimidamidoethylsulfanyl)-2,3-dihydro-1H-pyrrole -5-carboxylic acid, CHLORIDE ION, GLYCEROL, ...
著者Feng, H, Wang, D, Liu, W.
登録日2017-11-01
公開日2018-02-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The mechanism of NDM-1-catalyzed carbapenem hydrolysis is distinct from that of penicillin or cephalosporin hydrolysis.
Nat Commun, 8, 2017
5YPK
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Crystal structure of NDM-1 bound to hydrolyzed imipenem representing an EI2 complex
分子名称: (2R,4S)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-[(2-{[(Z)-iminomethyl]amino}ethyl)sulfanyl]-3,4-dihydro-2H-pyrrole-5-ca rboxylic acid, CHLORIDE ION, Metallo-beta-lactamase NDM-1, ...
著者Feng, H, Wang, D, Liu, W.
登録日2017-11-02
公開日2018-02-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The mechanism of NDM-1-catalyzed carbapenem hydrolysis is distinct from that of penicillin or cephalosporin hydrolysis.
Nat Commun, 8, 2017
5YPN
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Crystal structure of NDM-1 bound to hydrolyzed meropenem representing an EI2 complex
分子名称: (2~{S},3~{R},4~{S})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3~{S},5~{S})-5-(dimethylcarbamoy l)pyrrolidin-3-yl]sulfanyl-3-methyl-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid, Metallo-beta-lactamase NDM-1, SULFATE ION, ...
著者Feng, H, Liu, W, Wang, D.
登録日2017-11-02
公開日2018-02-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献The mechanism of NDM-1-catalyzed carbapenem hydrolysis is distinct from that of penicillin or cephalosporin hydrolysis.
Nat Commun, 8, 2017
5YPL
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Crystal structure of NDM-1 bound to hydrolyzed imipenem representing an EP complex
分子名称: (2R,4S)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-[(2-{[(Z)-iminomethyl]amino}ethyl)sulfanyl]-3,4-dihydro-2H-pyrrole-5-ca rboxylic acid, CHLORIDE ION, Metallo-beta-lactamase NDM-1, ...
著者Feng, H, Wang, D, Liu, W.
登録日2017-11-02
公開日2018-02-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The mechanism of NDM-1-catalyzed carbapenem hydrolysis is distinct from that of penicillin or cephalosporin hydrolysis.
Nat Commun, 8, 2017
5YPM
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BU of 5ypm by Molmil
Crystal structure of NDM-1 bound to hydrolyzed meropenem representing an EI1 complex
分子名称: (2S,3R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfan yl-3-methyl-2,3-dihydro-1H-pyrrole-5-carboxylic acid, Metallo-beta-lactamase NDM-1, SULFATE ION, ...
著者Feng, H, Wang, D, Liu, W.
登録日2017-11-02
公開日2018-02-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The mechanism of NDM-1-catalyzed carbapenem hydrolysis is distinct from that of penicillin or cephalosporin hydrolysis.
Nat Commun, 8, 2017
8GQW
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BU of 8gqw by Molmil
The Crystal Structures of a Swine SLA-2*HB01 Molecules Complexed with a CTL epitope from Asia1 serotype of Foot-and-mouth disease virus
分子名称: Hu64, MHC class I antigen, beta 2 microglobulin
著者Feng, L, Gao, Y.Y, Sun, M.W, Li, Z.B, Zhang, Q, Yang, J, Qiao, C, Jin, H, Feng, H.S, Xian, Y.H, Qi, J.X, Gao, G.F, Liu, W.J, Gao, F.S.
登録日2022-08-31
公開日2023-01-11
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献The Parallel Presentation of Two Functional CTL Epitopes Derived from the O and Asia 1 Serotypes of Foot-and-Mouth Disease Virus and Swine SLA-2*HB01: Implications for Universal Vaccine Development.
Cells, 11, 2022
8GQV
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The Crystal Structures of a Swine SLA-2*HB01 Molecules Complexed with a CTL epitope from Asia1 serotype of Foot-and-mouth disease virus
分子名称: As64, MHC class I antigen, beta 2 microglobulin
著者Feng, L, Gao, Y.Y, Sun, M.W, Li, Z.B, Zhang, Q, Yang, J, Qiao, C, Jin, H, Feng, H.S, Xian, Y.H, Qi, J.X, Gao, G.F, Liu, W.J, Gao, F.S.
登録日2022-08-31
公開日2023-01-11
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Parallel Presentation of Two Functional CTL Epitopes Derived from the O and Asia 1 Serotypes of Foot-and-Mouth Disease Virus and Swine SLA-2*HB01: Implications for Universal Vaccine Development.
Cells, 11, 2022
2AXL
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BU of 2axl by Molmil
Solution structure of a multifunctional DNA- and protein-binding domain of human Werner syndrome protein
分子名称: Werner syndrome
著者Hu, J.-S, Feng, H, Zeng, W, Lin, G.-X, Xi, X.G.
登録日2005-09-05
公開日2005-12-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of a multifunctional DNA- and protein-binding motif of human Werner syndrome protein.
Proc.Natl.Acad.Sci.Usa, 102, 2005
2RPI
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BU of 2rpi by Molmil
The NMR structure of the submillisecond folding intermediate of the Thermus thermophilus ribonuclease H
分子名称: Ribonuclease H
著者Zhou, Z, Feng, H, Bai, Y.
登録日2008-05-16
公開日2009-03-31
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The high-resolution NMR structure of the early folding intermediate of the Thermus thermophilus ribonuclease H
J.Mol.Biol., 384, 2008
7BYF
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BU of 7byf by Molmil
The crystal structure of mouse ORF10-Rae1-Nup98 complex
分子名称: 10 protein, MERCURY (II) ION, Peptidase S59 domain-containing protein, ...
著者Gao, P, Feng, H.
登録日2020-04-22
公開日2021-03-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular mechanism underlying selective inhibition of mRNA nuclear export by herpesvirus protein ORF10.
Proc.Natl.Acad.Sci.USA, 117, 2020
1DG4
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BU of 1dg4 by Molmil
NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK IN THE APO FORM
分子名称: DNAK
著者Pellecchia, M, Montgomery, D.L, Stevens, S.Y, Van der Kooi, C.W, Feng, H, Gierasch, L.M, Zuiderweg, E.R.P.
登録日1999-11-23
公開日1999-12-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural insights into substrate binding by the molecular chaperone DnaK.
Nat.Struct.Biol., 7, 2000
8K4B
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BU of 8k4b by Molmil
Cryo-EM structure of nucleotide-bound ComA with ZinC ion
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Competence factor transporting ATP-binding protein/permease ComA, ZINC ION
著者Yu, L, Xin, X, Min, L, Feng, H.
登録日2023-07-17
公開日2023-10-11
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis of peptide secretion for Quorum sensing by ComA.
Nat Commun, 14, 2023
2JSS
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NMR structure of chaperone Chz1 complexed with histone H2A.Z-H2B
分子名称: Chimera of Histone H2B.1 and Histone H2A.Z, Uncharacterized protein YER030W
著者Zhou, Z, Feng, H, Hansen, D.F, Kato, H, Luk, E, Freedberg, D.I, Kay, L.E, Wu, C, Bai, Y.
登録日2007-07-11
公開日2008-05-20
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献NMR structure of chaperone Chz1 complexed with histones H2A.Z-H2B.
Nat.Struct.Mol.Biol., 15, 2008
2L5A
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Structural basis for recognition of centromere specific histone H3 variant by nonhistone Scm3
分子名称: Histone H3-like centromeric protein CSE4, Protein SCM3, Histone H4
著者Zhou, Z, Feng, H, Zhou, B, Ghirlando, R, Hu, K, Zwolak, A, Jenkins, L, Xiao, H, Tjandra, N, Wu, C, Bai, Y.
登録日2010-10-28
公開日2011-03-16
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural basis for recognition of centromere histone variant CenH3 by the chaperone Scm3.
Nature, 472, 2011
7YVC
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Aplysia californica FaNaC in apo state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Chen, Q.F, Liu, F.L, Dang, Y, Feng, H, Zhang, Z, Ye, S.
登録日2022-08-19
公開日2023-08-09
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure and mechanism of a neuropeptide-activated channel in the ENaC/DEG superfamily.
Nat.Chem.Biol., 19, 2023

 

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