3GVQ
| UROD single-chain dimer | 分子名称: | Uroporphyrinogen decarboxylase | 著者 | Hill, C.P, Phillips, J.D, Warby, C, Whitby, F.G, Kushner, J.P. | 登録日 | 2009-03-31 | 公開日 | 2009-07-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Substrate shuttling between active sites of uroporphyrinogen decarboxylase is not required to generate coproporphyrinogen. J.Mol.Biol., 389, 2009
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3GW0
| UROD mutant G318R | 分子名称: | Uroporphyrinogen decarboxylase | 著者 | Hill, C.P, Phillips, J.D, Whitby, F.G, Warby, C, Kushner, J.P. | 登録日 | 2009-03-31 | 公開日 | 2009-07-07 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural and kinetic characterization of mutant human uroporphyrinogen decarboxylases. Cell Mol Biol (Noisy-le-grand), 55, 2009
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6FF9
| Mutant R280K of human P53 | 分子名称: | Cellular tumor antigen p53, ZINC ION | 著者 | Trovao, F.G, Gomes, A.S, Pinheiro, B, Carvalho, A.L, Romao, M.J. | 登録日 | 2018-01-04 | 公開日 | 2018-04-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Crystal Structure of the R280K Mutant of Human p53 Explains the Loss of DNA Binding. Int J Mol Sci, 19, 2018
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6G0V
| Human Galectin-3 in complex with a TF tumor-associated antigen mimetic | 分子名称: | (3~{R},5~{R},6~{S},7~{S},8~{R},13~{S})-5-(hydroxymethyl)-7-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-6-oxidanyl-11-oxidanylidene-2,4-dioxa-9-thia-12-azatricyclo[8.4.0.0^{3,8}]tetradec-1(10)-ene-13-carboxylic acid, CHLORIDE ION, Galectin-3 | 著者 | Trovao, F.G, Santarsia, S, Carvalho, A.L. | 登録日 | 2018-03-19 | 公開日 | 2018-08-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | 主引用文献 | Molecular Recognition of a Thomsen-Friedenreich Antigen Mimetic Targeting Human Galectin-3. ChemMedChem, 13, 2018
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5H5Z
| Crystal structure of bony fish MHC class I, peptide and B2m II | 分子名称: | Beta-2-microglobulin, MHC class I antigen, peptide chain | 著者 | Chen, Z, Zhang, N, Qi, J, Li, X, Chen, R, Wang, Z, Gao, F.G, Xia, C. | 登録日 | 2016-11-10 | 公開日 | 2017-11-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | The Mechanism of beta 2m Molecule-Induced Changes in the Peptide Presentation Profile in a Bony Fish. Iscience, 23, 2020
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8B6Z
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8B6L
| Subtomogram average of the human Sec61-TRAP-OSTA-translocon | 分子名称: | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2, ... | 著者 | Gemmer, M, Fedry, J.M.M, Forster, F.G. | 登録日 | 2022-09-27 | 公開日 | 2022-12-07 | 最終更新日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (7.6 Å) | 主引用文献 | Visualization of translation and protein biogenesis at the ER membrane. Nature, 614, 2023
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3U4R
| Novel HCV NS5B polymerase Inhibitors: Discovery of Indole C2 Acyl sulfonamides | 分子名称: | 1-[(2-aminopyridin-4-yl)methyl]-5-chloro-N-({3-[(methylsulfonyl)amino]phenyl}sulfonyl)-3-(2-oxo-1,2-dihydropyridin-3-yl)-1H-indole-2-carboxamide, RNA-directed RNA polymerase | 著者 | Anilkumar, G.N, Selyutin, O, Rosenblum, S.B, Zeng, Q, Jiang, Y, Chan, T.-Y, Pu, H, Wang, L, Bennett, F, Chen, K.X, Lesburg, C.A, Duca, J.S, Gavalas, S, Huang, Y, Pinto, P, Sannagrahi, M, Velazquez, F, Venkataraman, S, Vilbubhan, B, Agrawal, S, Ferrari, E, Jiang, C.-K, Huang, H.-C, Shih, N.-Y, Njoroge, F.G, Kozlowski, J.A. | 登録日 | 2011-10-10 | 公開日 | 2011-12-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | II. Novel HCV NS5B polymerase inhibitors: Discovery of indole C2 acyl sulfonamides. Bioorg.Med.Chem.Lett., 22, 2012
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3U4O
| Novel HCV NS5B polymerase Inhibitors: Discovery of Indole C2 Acyl sulfonamides | 分子名称: | 1-[(2-aminopyridin-4-yl)methyl]-5-chloro-3-(2-oxo-1,2-dihydropyridin-3-yl)-1H-indole-2-carboxylic acid, PHOSPHATE ION, RNA-directed RNA polymerase | 著者 | Anilkumar, G.N, Selyutin, O, Rosenblum, S.B, Zeng, Q, Jiang, Y, Chan, T.-Y, Pu, H, Wang, L, Bennett, F, Chen, K.X, Lesburg, C.A, Duca, J.S, Gavalas, S, Huang, Y, Pinto, P, Sannigrahi, M, Velazquez, F, Venkataraman, S, Vilbubhan, B, Agrawal, S, Ferrari, E, Jiang, C.-K, Huang, H.-C, Shih, N.-Y, Njoroge, F.G, Kozlowski, J.A. | 登録日 | 2011-10-10 | 公開日 | 2011-12-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | II. Novel HCV NS5B polymerase inhibitors: Discovery of indole C2 acyl sulfonamides. Bioorg.Med.Chem.Lett., 22, 2012
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5XL6
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4PBO
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5XLD
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5XL9
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4QZV
| Bat-derived coronavirus HKU4 uses MERS-CoV receptor human CD26 for cell entry | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4, ... | 著者 | Gao, F.G, Wang, Q.H, Qi, J.X, Lu, G.W. | 登録日 | 2014-07-29 | 公開日 | 2014-10-29 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.592 Å) | 主引用文献 | Bat Origins of MERS-CoV Supported by Bat Coronavirus HKU4 Usage of Human Receptor CD26. Cell Host Microbe, 16, 2014
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4PBP
| crystal structure of zebrafish short-chain pentraxin protein | 分子名称: | C-reactive protein, CALCIUM ION, GLYCEROL | 著者 | Chen, R, Qi, J.X, George, F.G, Xia, C. | 登録日 | 2014-04-13 | 公開日 | 2015-03-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.648 Å) | 主引用文献 | Crystal structures for short-chain pentraxin from zebrafish demonstrate a cyclic trimer with new recognition and effector faces. J.Struct.Biol., 189, 2015
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5XL1
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7WBL
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7XCP
| Cryo-EM structure of Omicron RBD complexed with ACE2 and 304 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 304 Fab, ... | 著者 | Zhao, Z, Qi, J, Gao, F.G. | 登録日 | 2022-03-24 | 公開日 | 2022-08-31 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape Nat Commun, 13, 2022
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7C01
| Molecular basis for a potent human neutralizing antibody targeting SARS-CoV-2 RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CB6 heavy chain, CB6 light chain, ... | 著者 | Shi, R, Qi, J, Wang, Q, Gao, F.G, Yan, J. | 登録日 | 2020-04-29 | 公開日 | 2020-05-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | A human neutralizing antibody targets the receptor-binding site of SARS-CoV-2. Nature, 584, 2020
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7BSD
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7BSC
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6J2A
| The structure of HLA-A*3003/NP44 | 分子名称: | Beta-2-microglobulin, HLA-A*3003, NP44 | 著者 | Zhu, S.Y, Liu, K.F, Chai, Y, Ding, C.M, Lv, J.X, Gao, F.G, Lou, Y.L, Liu, W.J. | 登録日 | 2018-12-31 | 公開日 | 2019-09-25 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides. Front Immunol, 10, 2019
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6J9O
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6J29
| The structure of HLA-A*3003/MTB | 分子名称: | Beta-2-microglobulin, HLA-A*3003, MTB | 著者 | Zhu, S.Y, Liu, K.F, Chai, Y, Ding, C.M, Lv, J.X, Gao, F.G, Lou, Y.L, Liu, W.J. | 登録日 | 2018-12-31 | 公開日 | 2019-09-25 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides. Front Immunol, 10, 2019
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6JO8
| The complex structure of CHIKV envelope glycoprotein bound to human MXRA8 | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHIKV E1, ... | 著者 | Song, H, Zhao, Z, Qi, J, Gao, F, Gao, F.G. | 登録日 | 2019-03-20 | 公開日 | 2019-05-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.495 Å) | 主引用文献 | Molecular Basis of Arthritogenic Alphavirus Receptor MXRA8 Binding to Chikungunya Virus Envelope Protein. Cell, 177, 2019
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