7C01

Molecular basis for a potent human neutralizing antibody targeting SARS-CoV-2 RBD

Summary for 7C01

Entry DOI	10.2210/pdb7c01/pdb
Descriptor	Spike protein S1, CB6 heavy chain, CB6 light chain, ... (4 entities in total)
Functional Keywords	sars-cov-2, rbd, neutralizing antibodies, molecular basis, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More
Total number of polymer chains	6
Total formula weight	149683.28
Authors	Shi, R.,Qi, J.,Wang, Q.,Gao, F.G.,Yan, J. (deposition date: 2020-04-29, release date: 2020-05-27, Last modification date: 2023-11-29)
Primary citation	Shi, R.,Shan, C.,Duan, X.,Chen, Z.,Liu, P.,Song, J.,Song, T.,Bi, X.,Han, C.,Wu, L.,Gao, G.,Hu, X.,Zhang, Y.,Tong, Z.,Huang, W.,Liu, W.J.,Wu, G.,Zhang, B.,Wang, L.,Qi, J.,Feng, H.,Wang, F.S.,Wang, Q.,Gao, G.F.,Yuan, Z.,Yan, J. A human neutralizing antibody targets the receptor-binding site of SARS-CoV-2. Nature, 584:120-124, 2020 Cited by PubMed: 32454512 DOI: 10.1038/s41586-020-2381-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.88 Å)

Structure validation