7C01

Molecular basis for a potent human neutralizing antibody targeting SARS-CoV-2 RBD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, B)	Spike protein S1	polymer	229	25951.2	2	UniProt (P0DTC2) Pfam (PF09408)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	S glycoprotein,E2,Peplomer protein,SARS-Cov-2 Spike protein S1
2	B, E (H, C)	CB6 heavy chain	polymer	233	24950.9	2		Homo sapiens
3	C, F (L, D)	CB6 light chain	polymer	217	23718.3	2		Homo sapiens
4	G, H (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)

Sequence modifications

A, B: 319 - 541 (UniProt: P0DTC2)

PDB	External Database	Details
His 542	-	expression tag
His 543	-	expression tag
His 544	-	expression tag
His 545	-	expression tag
His 546	-	expression tag
His 547	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	149240.9
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	149683.3

*Water molecules are not included.