6J9O

Crystal structure of a free scFv molecule from a group 2 influenza A viruses HA binding antibody AF4H1K1

Summary for 6J9O

Entry DOI	10.2210/pdb6j9o/pdb
Descriptor	Heavy chain of AF4H1K1 scFv, Light chain of AF4H1K1 scFv (3 entities in total)
Functional Keywords	a free scfv molecule, af4h1k1, influenza a viruses, ha binding antibody, antiviral protein
Biological source	Homo sapiens More
Total number of polymer chains	2
Total formula weight	26093.04
Authors	Xiao, H.X.,Qi, J.X.,Gao, F.G. (deposition date: 2019-01-23, release date: 2020-01-29, Last modification date: 2021-02-10)
Primary citation	Xiao, H.,Guo, T.,Yang, M.,Qi, J.,Huang, C.,Hong, Y.,Gu, J.,Pang, X.,Liu, W.J.,Peng, R.,McCauley, J.,Bi, Y.,Li, S.,Feng, J.,Zhang, H.,Zhang, X.,Lu, X.,Yan, J.,Chen, L.,Shi, Y.,Chen, W.,Gao, G.F. Light chain modulates heavy chain conformation to change protection profile of monoclonal antibodies against influenza A viruses. Cell Discov, 5:21-21, 2019 Cited by PubMed: 30993000 DOI: 10.1038/s41421-019-0086-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.397 Å)

Structure validation