7BSC

Complex structure of 1G5.3 Fab bound to DENV2 NS1c

Summary for 7BSC

• Entry DOI: 10.2210/pdb7bsc/pdb
• Descriptor: Non-structural protein 1, 1G5.3 Fab Heavy Chain, 1G5.3 Fab Light Chain, ... (4 entities in total)
• Functional Keywords: dengue virus, ns1, antibody, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Dengue virus 2; More
• Total number of polymer chains: 3
• Total formula weight: 68666.06

Authors

Song, H.,Qi, J.,Gao, F.G. (deposition date: 2020-03-30, release date: 2020-12-23, Last modification date: 2023-11-29)

• Primary citation: Modhiran, N.,Song, H.,Liu, L.,Bletchly, C.,Brillault, L.,Amarilla, A.A.,Xu, X.,Qi, J.,Chai, Y.,Cheung, S.T.M.,Traves, R.,Setoh, Y.X.,Bibby, S.,Scott, C.A.P.,Freney, M.E.,Newton, N.D.,Khromykh, A.A.,Chappell, K.J.,Muller, D.A.,Stacey, K.J.,Landsberg, M.J.,Shi, Y.,Gao, G.F.,Young, P.R.,Watterson, D.; A broadly protective antibody that targets the flavivirus NS1 protein.; Science, 371:190-194, 2021; PubMed: 33414219; DOI: 10.1126/science.abb9425

Experimental method

X-RAY DIFFRACTION (2.31 Å)