3GW0

UROD mutant G318R

Summary for 3GW0

Entry DOI	10.2210/pdb3gw0/pdb
Related	1uro
Descriptor	Uroporphyrinogen decarboxylase (2 entities in total)
Functional Keywords	uroporphyrinogen, decarboxylase, lyase, heme biosynthesis. porphyria, disease mutation, heme biosynthesis, phosphoprotein, porphyrin biosynthesis
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm: P06132
Total number of polymer chains	1
Total formula weight	40931.91
Authors	Hill, C.P.,Phillips, J.D.,Whitby, F.G.,Warby, C.,Kushner, J.P. (deposition date: 2009-03-31, release date: 2009-07-07, Last modification date: 2024-02-21)
Primary citation	Warby, C.A.,Phillips, J.D.,Bergonia, H.A.,Whitby, F.G.,Hill, C.P.,Kushner, J.P. Structural and kinetic characterization of mutant human uroporphyrinogen decarboxylases. Cell Mol Biol (Noisy-le-grand), 55:40-45, 2009 Cited by PubMed: 19656450 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation