3GVQ
UROD single-chain dimer
Summary for 3GVQ
Entry DOI | 10.2210/pdb3gvq/pdb |
Related | 1uro 3GVR 3GVV 3GVW |
Descriptor | Uroporphyrinogen decarboxylase (2 entities in total) |
Functional Keywords | heme, uroporphyrinogen, decarboxylase, alpha-8-beta-8 barrel, lyase, acetylation, cytoplasm, disease mutation, heme biosynthesis, phosphoprotein, porphyrin biosynthesis |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: P06132 |
Total number of polymer chains | 1 |
Total formula weight | 40831.77 |
Authors | Hill, C.P.,Phillips, J.D.,Warby, C.,Whitby, F.G.,Kushner, J.P. (deposition date: 2009-03-31, release date: 2009-07-07, Last modification date: 2023-09-06) |
Primary citation | Phillips, J.D.,Warby, C.A.,Whitby, F.G.,Kushner, J.P.,Hill, C.P. Substrate shuttling between active sites of uroporphyrinogen decarboxylase is not required to generate coproporphyrinogen. J.Mol.Biol., 389:306-314, 2009 Cited by PubMed: 19362562DOI: 10.1016/j.jmb.2009.04.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report