6U2G
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![BU of 6u2g by Molmil](/molmil-images/mine/6u2g) | BRAF-MEK complex with AMP-PCP bound to BRAF | Descriptor: | Dual specificity mitogen-activated protein kinase kinase 1, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | Authors: | Liau, N.P.D, Wendorff, T, Hymowitz, S, Sudhamsu, J. | Deposit date: | 2019-08-19 | Release date: | 2019-08-28 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.886 Å) | Cite: | Negative regulation of RAF kinase activity by ATP is overcome by 14-3-3-induced dimerization. Nat.Struct.Mol.Biol., 27, 2020
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7R5S
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![BU of 7r5s by Molmil](/molmil-images/mine/7r5s) | Structure of the human CCAN bound to alpha satellite DNA | Descriptor: | Centromere protein H, Centromere protein I, Centromere protein K, ... | Authors: | Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D. | Deposit date: | 2022-02-11 | Release date: | 2022-04-27 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.83 Å) | Cite: | Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome. Science, 376, 2022
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7R5R
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![BU of 7r5r by Molmil](/molmil-images/mine/7r5r) | Structure of the human CCAN CENP-A alpha-satellite complex | Descriptor: | Centromere protein C, DNA (171-MER), Histone H2A type 1-C, ... | Authors: | Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D. | Deposit date: | 2022-02-11 | Release date: | 2022-04-27 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.44 Å) | Cite: | Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome. Science, 376, 2022
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7R5V
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![BU of 7r5v by Molmil](/molmil-images/mine/7r5v) | Structure of the human CCAN CENP-A alpha-satellite complex | Descriptor: | Centromere protein H, Centromere protein I, Centromere protein K, ... | Authors: | Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D. | Deposit date: | 2022-02-11 | Release date: | 2022-04-27 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.55 Å) | Cite: | Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome. Science, 376, 2022
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9ATK
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7AU2
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![BU of 7au2 by Molmil](/molmil-images/mine/7au2) | Cryo-EM structure of human exostosin-like 3 (EXTL3) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Exostosin-like 3, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Wilson, L.F.L, Dendooven, T, Hardwick, S.W, Chirgadze, D.Y, Luisi, B.F, Logan, D.T, Mani, K, Dupree, P. | Deposit date: | 2020-11-02 | Release date: | 2022-05-18 | Last modified: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (2.43 Å) | Cite: | The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis. Nat Commun, 13, 2022
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7AUA
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![BU of 7aua by Molmil](/molmil-images/mine/7aua) | Cryo-EM structure of human exostosin-like 3 (EXTL3) in complex with UDP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Exostosin-like 3, MANGANESE (II) ION, ... | Authors: | Wilson, L.F.L, Dendooven, T, Hardwick, S.W, Chirgadze, D.Y, Luisi, B.F, Logan, D.T, Mani, K, Dupree, P. | Deposit date: | 2020-11-02 | Release date: | 2022-05-18 | Last modified: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis. Nat Commun, 13, 2022
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9ASX
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5OSN
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![BU of 5osn by Molmil](/molmil-images/mine/5osn) | Crystal Structure of Bovine Enterovirus 2 determined with Serial Femtosecond X-ray Crystallography | Descriptor: | Capsid protein, GLUTAMIC ACID, POTASSIUM ION, ... | Authors: | Roedig, P, Ginn, H.M, Pakendorf, T, Sutton, G, Harlos, K, Walter, T.S, Meyer, J, Fischer, P, Duman, R, Vartiainen, I, Reime, B, Warmer, M, Brewster, A.S, Young, I.D, Michels-Clark, T, Sauter, N.K, Kotecha, A, Kelly, J, Rowlands, D.J, Sikorsky, M, Nelson, S, Damiani, D.S, Alonso-Mori, R, Ren, J, Fry, E.E, David, C, Stuart, D.I, Wagner, A, Meents, A. | Deposit date: | 2017-08-17 | Release date: | 2017-08-30 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | High-speed fixed-target serial virus crystallography. Nat. Methods, 14, 2017
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6QF1
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![BU of 6qf1 by Molmil](/molmil-images/mine/6qf1) | X-Ray structure of Proteinase K crystallized on a silicon chip | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CALCIUM ION, Proteinase K | Authors: | Lieske, J, Cerv, M, Kreida, S, Barthelmess, M, Fischer, P, Pakendorf, T, Yefanov, O, Mariani, V, Seine, T, Ross, B.H, Crosas, E, Lorbeer, O, Burkhardt, A, Lane, T.J, Guenther, S, Bergtholdt, J, Schoen, S, Tornroth-Horsefield, S, Chapman, H.N, Meents, A. | Deposit date: | 2019-01-09 | Release date: | 2019-07-10 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.737 Å) | Cite: | On-chip crystallization for serial crystallography experiments and on-chip ligand-binding studies. Iucrj, 6, 2019
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6O1L
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![BU of 6o1l by Molmil](/molmil-images/mine/6o1l) | Architectural principles for Hfq/Crc-mediated regulation of gene expression Hfq-Crc-amiE 2:3:2 complex | Descriptor: | Catabolite repression control protein, RNA (5'-R(*AP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*CP*AP*AP*GP*AP*GP*G)-3'), RNA-binding protein Hfq | Authors: | Pei, X.Y, Dendooven, T, Sonnleitner, E, Chen, S, Blasi, U, Luisi, B.F. | Deposit date: | 2019-02-20 | Release date: | 2019-03-13 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Architectural principles for Hfq/Crc-mediated regulation of gene expression. Elife, 8, 2019
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6O1K
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![BU of 6o1k by Molmil](/molmil-images/mine/6o1k) | Architectural principles for Hfq/Crc-mediated regulation of gene expression. Hfq-Crc-amiE 2:2:2 complex (core complex) | Descriptor: | Catabolite repression control protein, RNA (5'-R(*AP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*CP*AP*AP*GP*AP*GP*G)-3'), RNA-binding protein Hfq | Authors: | Pei, X.Y, Dendooven, T, Sonnleitner, E, Chen, S, Blasi, U, Luisi, B.F. | Deposit date: | 2019-02-20 | Release date: | 2019-03-13 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.13 Å) | Cite: | Architectural principles for Hfq/Crc-mediated regulation of gene expression Elife, 8, 2019
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6QF2
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![BU of 6qf2 by Molmil](/molmil-images/mine/6qf2) | X-Ray structure of Thermolysin crystallized on a silicon chip | Descriptor: | 1,2-ETHANEDIOL, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, CALCIUM ION, ... | Authors: | Lieske, J, Cerv, M, Kreida, S, Barthelmess, M, Fischer, P, Pakendorf, T, Yefanov, O, Mariani, V, Seine, T, Ross, B.H, Crosas, E, Lorbeer, O, Burkhardt, A, Lane, T.J, Guenther, S, Bergtholdt, J, Schoen, S, Tornroth-Horsefield, S, Chapman, H.N, Meents, A. | Deposit date: | 2019-01-09 | Release date: | 2019-07-10 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.733 Å) | Cite: | On-chip crystallization for serial crystallography experiments and on-chip ligand-binding studies. Iucrj, 6, 2019
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6QF3
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![BU of 6qf3 by Molmil](/molmil-images/mine/6qf3) | X-Ray structure of Thermolysin soaked with sodium aspartate on a silicon chip | Descriptor: | 1,2-ETHANEDIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ASPARTIC ACID, ... | Authors: | Lieske, J, Cerv, M, Kreida, S, Barthelmess, M, Fischer, P, Pakendorf, T, Yefanov, O, Mariani, V, Seine, T, Ross, B.H, Crosas, E, Lorbeer, O, Burkhardt, A, Lane, T.J, Guenther, S, Bergtholdt, J, Schoen, S, Tornroth-Horsefield, S, Chapman, H.N, Meents, A. | Deposit date: | 2019-01-09 | Release date: | 2019-07-10 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.521 Å) | Cite: | On-chip crystallization for serial crystallography experiments and on-chip ligand-binding studies. Iucrj, 6, 2019
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6QF4
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![BU of 6qf4 by Molmil](/molmil-images/mine/6qf4) | X-Ray structure of human Serine/Threonine Kinase 17B (STK17B) aka DRAK2 in complex with ADP obtained by on-chip soaking | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Lieske, J, Cerv, M, Kreida, S, Barthelmess, M, Fischer, P, Pakendorf, T, Yefanov, O, Mariani, V, Seine, T, Ross, B.H, Crosas, E, Lorbeer, O, Burkhardt, A, Lane, T.J, Guenther, S, Bergtholdt, J, Schoen, S, Tornroth-Horsefield, S, Chapman, H.N, Meents, A. | Deposit date: | 2019-01-09 | Release date: | 2019-07-10 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.495 Å) | Cite: | On-chip crystallization for serial crystallography experiments and on-chip ligand-binding studies. Iucrj, 6, 2019
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6QF5
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![BU of 6qf5 by Molmil](/molmil-images/mine/6qf5) | X-Ray structure of human Aquaporin 2 crystallized on a silicon chip | Descriptor: | Aquaporin-2, CADMIUM ION | Authors: | Lieske, J, Cerv, M, Kreida, S, Barthelmess, M, Fischer, P, Pakendorf, T, Yefanov, O, Mariani, V, Seine, T, Ross, B.H, Crosas, E, Lorbeer, O, Burkhardt, A, Lane, T.J, Guenther, S, Bergtholdt, J, Schoen, S, Tornroth-Horsefield, S, Chapman, H.N, Meents, A. | Deposit date: | 2019-01-09 | Release date: | 2019-07-10 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | On-chip crystallization for serial crystallography experiments and on-chip ligand-binding studies. Iucrj, 6, 2019
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6O1M
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![BU of 6o1m by Molmil](/molmil-images/mine/6o1m) | Architectural principles for Hfq/Crc-mediated regulation of gene expression. Hfq-Crc-amiE 2:4:2 complex | Descriptor: | Catabolite repression control protein, RNA (5'-R(*AP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*CP*AP*AP*GP*AP*GP*G)-3'), RNA-binding protein Hfq | Authors: | Pei, X.Y, Dendooven, T, Sonnleitner, E, Chen, S, Blasi, U, Luisi, B.F. | Deposit date: | 2019-02-20 | Release date: | 2019-03-13 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Architectural principles for Hfq/Crc-mediated regulation of gene expression. Elife, 8, 2019
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5NYU
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![BU of 5nyu by Molmil](/molmil-images/mine/5nyu) | M2 G-quadruplex 10 wt% PEG8000 | Descriptor: | DNA (5'-D(*TP*AP*GP*GP*GP*AP*CP*GP*GP*GP*CP*GP*GP*GP*CP*AP*GP*GP*GP*T)-3') | Authors: | Trajkovski, M, Plavec, J, Endoh, T, Tateishi-Karimata, H, Sugimoto, N. | Deposit date: | 2017-05-11 | Release date: | 2018-04-11 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Pursuing origins of (poly)ethylene glycol-induced G-quadruplex structural modulations. Nucleic Acids Res., 46, 2018
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5NYS
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![BU of 5nys by Molmil](/molmil-images/mine/5nys) | M2 G-quadruplex dilute solution | Descriptor: | DNA (5'-D(*TP*AP*GP*GP*GP*AP*CP*GP*GP*GP*CP*GP*GP*GP*CP*AP*GP*GP*GP*T)-3') | Authors: | Trajkovski, M, Plavec, J, Endoh, T, Tateishi-Karimata, H, Sugimoto, N. | Deposit date: | 2017-05-11 | Release date: | 2018-04-11 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Pursuing origins of (poly)ethylene glycol-induced G-quadruplex structural modulations. Nucleic Acids Res., 46, 2018
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5NYT
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![BU of 5nyt by Molmil](/molmil-images/mine/5nyt) | M2 G-quadruplex 20 wt% ethylene glycol | Descriptor: | DNA (5'-D(*TP*AP*GP*GP*GP*AP*CP*GP*GP*GP*CP*GP*GP*GP*CP*AP*GP*GP*GP*T)-3') | Authors: | Trajkovski, M, Plavec, J, Endoh, T, Tateishi-Karimata, H, Sugimoto, N. | Deposit date: | 2017-05-11 | Release date: | 2018-04-11 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Pursuing origins of (poly)ethylene glycol-induced G-quadruplex structural modulations. Nucleic Acids Res., 46, 2018
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8D4S
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![BU of 8d4s by Molmil](/molmil-images/mine/8d4s) | Crystal Structure of Cathepsin G Inhibited by Eap1 from S. aureus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cathepsin G, C-terminal truncated form, ... | Authors: | Gido, C.D, Herdendorf, T.J, Geisbrecht, B.V. | Deposit date: | 2022-06-02 | Release date: | 2022-12-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Characterization of two distinct neutrophil serine protease-binding modes within a Staphylococcus aureus innate immune evasion protein family. J.Biol.Chem., 299, 2023
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8D4V
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![BU of 8d4v by Molmil](/molmil-images/mine/8d4v) | Crystal Structure of Cathepsin G Inhibited by Eap2 from S. aureus | Descriptor: | Cathepsin G, C-terminal truncated form, Extracellular Adherence Protein, ... | Authors: | Gido, C.D, Herdendorf, T.J, Geisbrecht, B.V. | Deposit date: | 2022-06-02 | Release date: | 2022-12-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Characterization of two distinct neutrophil serine protease-binding modes within a Staphylococcus aureus innate immune evasion protein family. J.Biol.Chem., 299, 2023
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8D7I
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8D7K
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3D4J
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![BU of 3d4j by Molmil](/molmil-images/mine/3d4j) | Crystal structure of Human mevalonate diphosphate decarboxylase | Descriptor: | Diphosphomevalonate decarboxylase, SULFATE ION | Authors: | Voynova, N.E, Fu, Z, Battaile, K, Herdendorf, T.J, Kim, J.-J.P, Miziorko, H.M. | Deposit date: | 2008-05-14 | Release date: | 2008-12-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Human mevalonate diphosphate decarboxylase: characterization, investigation of the mevalonate diphosphate binding site, and crystal structure. Arch.Biochem.Biophys., 480, 2008
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