6QF4

X-Ray structure of human Serine/Threonine Kinase 17B (STK17B) aka DRAK2 in complex with ADP obtained by on-chip soaking

Summary for 6QF4

Entry DOI	10.2210/pdb6qf4/pdb
Related	6QF1 6QF2 6QF3
Descriptor	Serine/threonine-protein kinase 17B, MAGNESIUM ION, CHLORIDE ION, ... (7 entities in total)
Functional Keywords	stk17b, drak2, adp, on-chip ligand soaking, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	37935.16
Authors	Lieske, J.,Cerv, M.,Kreida, S.,Barthelmess, M.,Fischer, P.,Pakendorf, T.,Yefanov, O.,Mariani, V.,Seine, T.,Ross, B.H.,Crosas, E.,Lorbeer, O.,Burkhardt, A.,Lane, T.J.,Guenther, S.,Bergtholdt, J.,Schoen, S.,Tornroth-Horsefield, S.,Chapman, H.N.,Meents, A. (deposition date: 2019-01-09, release date: 2019-07-10, Last modification date: 2024-01-24)
Primary citation	Lieske, J.,Cerv, M.,Kreida, S.,Komadina, D.,Fischer, J.,Barthelmess, M.,Fischer, P.,Pakendorf, T.,Yefanov, O.,Mariani, V.,Seine, T.,Ross, B.H.,Crosas, E.,Lorbeer, O.,Burkhardt, A.,Lane, T.J.,Guenther, S.,Bergtholdt, J.,Schoen, S.,Tornroth-Horsefield, S.,Chapman, H.N.,Meents, A. On-chip crystallization for serial crystallography experiments and on-chip ligand-binding studies. Iucrj, 6:714-728, 2019 Cited by PubMed: 31316815 DOI: 10.1107/S2052252519007395 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.495 Å)

Structure validation