6QF4
X-Ray structure of human Serine/Threonine Kinase 17B (STK17B) aka DRAK2 in complex with ADP obtained by on-chip soaking
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase 17B | polymer | 327 | 37327.1 | 1 | UniProt (O94768) Pfam (PF00069) | Homo sapiens (Human) | DAP kinase-related apoptosis-inducing protein kinase 2 |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | E (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 6 | F (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 7 | G (A) | water | water | 18.0 | 122 | Chemie (HOH) |
Sequence modifications
A: 25 - 329 (UniProt: O94768)
| PDB | External Database | Details |
|---|---|---|
| Met 3 | - | initiating methionine |
| His 4 | - | expression tag |
| His 5 | - | expression tag |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| His 9 | - | expression tag |
| Ser 10 | - | linker |
| Ser 11 | - | linker |
| Gly 12 | - | linker |
| Val 13 | - | linker |
| Asp 14 | - | linker |
| Leu 15 | - | linker |
| Gly 16 | - | linker |
| Thr 17 | - | linker |
| Glu 18 | - | cloning artifact |
| Asn 19 | - | cloning artifact |
| Leu 20 | - | cloning artifact |
| Tyr 21 | - | cloning artifact |
| Phe 22 | - | cloning artifact |
| Gln 23 | - | cloning artifact |
| Ser 24 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37327.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 608.1 | |
| All* | Total formula weight | 37935.2 |
