2KHX
 
 | | Drosha double-stranded RNA binding motif | | 分子名称: | Ribonuclease 3 | | 著者 | Mueller, G.A, Miller, M, Ghosh, M, DeRose, E.F, London, R.E, Hall, T. | | 登録日 | 2009-04-13 | | 公開日 | 2010-02-23 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the Drosha double-stranded RNA-binding domain.
Silence, 1, 2010
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4EST
 | | CRYSTAL STRUCTURE OF THE COVALENT COMPLEX FORMED BY A PEPTIDYL ALPHA,ALPHA-DIFLUORO-BETA-KETO AMIDE WITH PORCINE PANCREATIC ELASTASE AT 1.78-ANGSTROMS RESOLUTION | | 分子名称: | CALCIUM ION, ELASTASE, INHIBITOR ACE-ALA-PRO-VAI-DIFLUORO-N-PHENYLETHYLACETAMIDE, ... | | 著者 | Takahashi, L.H, Radhakrishnan, R, Rosenfieldjunior, R.E, Meyerjunior, E.F, Trainor, D.A. | | 登録日 | 1989-05-15 | | 公開日 | 1992-04-15 | | 最終更新日 | 2018-10-03 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Crystal Structure of the Covalent Complex Formed by a Peptidyl Alpha,Alpha-Difluoro-Beta-Keto Amide with Porcine Pancreatic Elastase at 1.78-Angstroms Resolution
J.Am.Chem.Soc., 111, 1989
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2KNC
 | | Platelet integrin ALFAIIB-BETA3 transmembrane-cytoplasmic heterocomplex | | 分子名称: | Integrin alpha-IIb, Integrin beta-3 | | 著者 | Yang, J, Ma, Y, Page, R.C, Misra, S, Plow, E.F, Qin, J. | | 登録日 | 2009-08-20 | | 公開日 | 2009-09-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of an integrin alphaIIb beta3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation.
Proc.Natl.Acad.Sci.USA, 106, 2009
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2EAW
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2L7D
 | | Ribonucleotide Perturbation of DNA Structure: Solution Structure of [d(CGC)r(G)d(AATTCGCG)]2 | | 分子名称: | 5'-D(*CP*GP*C)-R(P*G)-D(P*AP*AP*TP*TP*CP*GP*CP*G)-3' | | 著者 | DeRose, E.F, Perera, L, Murray, M.S, Kunkel, T.A, London, R.E. | | 登録日 | 2010-12-07 | | 公開日 | 2011-06-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the Dickerson DNA dodecamer containing a single ribonucleotide.
Biochemistry, 51, 2012
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2E3T
 | | Crystal structure of rat xanthine oxidoreductase mutant (W335A and F336L) | | 分子名称: | BICARBONATE ION, CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Asai, R, Nishino, T, Matsumura, T, Okamoto, K, Pai, E.F, Nishino, T. | | 登録日 | 2006-11-28 | | 公開日 | 2007-09-25 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Two mutations convert mammalian xanthine oxidoreductase to highly superoxide-productive xanthine oxidase
J.Biochem.(Tokyo), 141, 2007
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2E6Y
 | | Covalent complex of orotidine 5'-monophosphate decarboxylase (ODCase) with 6-Iodo-UMP | | 分子名称: | GLYCEROL, Orotidine 5'-phosphate decarboxylase, URIDINE-5'-MONOPHOSPHATE | | 著者 | Fujihashi, M, Bello, A.M, Kotra, L.P, Pai, E.F. | | 登録日 | 2007-01-05 | | 公開日 | 2007-02-27 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | A Potent, Covalent Inhibitor of Orotidine 5'-Monophosphate Decarboxylase with Antimalarial Activity.
J.Med.Chem., 50, 2007
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2LGX
 | | NMR structure for Kindle-2 N-terminus | | 分子名称: | Fermitin family homolog 2 | | 著者 | Perera, H.D, Ma, Y, Yang, J, Hirbawi, J, Plow, E.F, Qin, J. | | 登録日 | 2011-08-03 | | 公開日 | 2011-11-30 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Membrane Binding of the N-Terminal Ubiquitin-Like Domain of kindlin-2 Is Crucial for Its Regulation of Integrin Activation.
Structure, 19, 2011
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2ESH
 | | Crystal Structure of Conserved Protein of Unknown Function TM0937- a Potential Transcriptional Factor | | 分子名称: | CALCIUM ION, conserved hypothetical protein TM0937 | | 著者 | Liu, Y, Bochkareva, E, Zheng, H, Xu, X, Nocek, B, Lunin, V, Edward, A, Pai, E.F, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2005-10-26 | | 公開日 | 2005-12-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structure of Conserved Hypothetical Protein TM0937
To be Published
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2Q9F
 | | Crystal structure of human cytochrome P450 46A1 in complex with cholesterol-3-sulphate | | 分子名称: | CHOLEST-5-EN-3-YL HYDROGEN SULFATE, Cytochrome P450 46A1, GLYCEROL, ... | | 著者 | White, M.A, Mast, N.V, Johnson, E.F, Stout, C.D, Pikuleva, I.A. | | 登録日 | 2007-06-12 | | 公開日 | 2008-06-17 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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2CG7
 | | SECOND AND THIRD FIBRONECTIN TYPE I MODULE PAIR (CRYSTAL FORM II). | | 分子名称: | FIBRONECTIN | | 著者 | Rudino-Pinera, E, Ravelli, R.B.G, Sheldrick, G.M, Nanao, M.H, Werner, J.M, Schwarz-Linek, U, Potts, J.R, Garman, E.F. | | 登録日 | 2006-02-27 | | 公開日 | 2007-02-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | The Solution and Crystal Structures of a Module Pair from the Staphylococcus Aureus-Binding Site of Human Fibronectin-A Tale with a Twist.
J.Mol.Biol., 368, 2007
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2FSE
 | | Crystallographic structure of a rheumatoid arthritis MHC susceptibility allele, HLA-DR1 (DRB1*0101), complexed with the immunodominant determinant of human type II collagen | | 分子名称: | Collagen alpha-1(II), H-2 class II histocompatibility antigen, E-K alpha chain, ... | | 著者 | Ivey, R.A, Rosloniec, E.F, Whittington, K.B, Kang, A.H, Park, H.W. | | 登録日 | 2006-01-22 | | 公開日 | 2006-09-19 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystallographic Structure of a Rheumatoid Arthritis MHC Susceptibility Allele, HLA-DR1 (DRB1*0101), Complexed with the Immunodominant Determinant of Human Type II Collagen.
J.Immunol., 177, 2006
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1NDA
 | | THE STRUCTURE OF TRYPANOSOMA CRUZI TRYPANOTHIONE REDUCTASE IN THE OXIDIZED AND NADPH REDUCED STATE | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, TRYPANOTHIONE OXIDOREDUCTASE | | 著者 | Lantwin, C.B, Kabsch, W, Pai, E.F, Schlichting, I, Krauth-Siegel, R.L. | | 登録日 | 1993-07-02 | | 公開日 | 1994-09-30 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | The structure of Trypanosoma cruzi trypanothione reductase in the oxidized and NADPH reduced state.
Proteins, 18, 1994
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2JM6
 | | Solution structure of MCL-1 complexed with NOXAB | | 分子名称: | Myeloid cell leukemia-1 protein Mcl-1 homolog, Noxa | | 著者 | Czabotar, P.E, Lee, E.F, van Delft, M.F, Day, C.L, Smith, B.J, Huang, D.C.S, Fairlie, W.D, Hinds, M.G, Colman, P.M. | | 登録日 | 2006-10-17 | | 公開日 | 2007-03-20 | | 最終更新日 | 2023-12-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural insights into the degradation of Mcl-1 induced by BH3 domains
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2FV2
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2JRZ
 | | Solution structure of the Bright/ARID domain from the human JARID1C protein. | | 分子名称: | Histone demethylase JARID1C | | 著者 | Koehler, C, Bishop, S, Dowler, E.F, Diehl, A, Schmieder, P, Leidert, M, Sundstrom, M, Arrowsmith, C.H, Wiegelt, J, Edwards, A, Oschkinat, H, Ball, L.J, Structural Genomics Consortium (SGC) | | 登録日 | 2007-06-29 | | 公開日 | 2007-07-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Backbone and sidechain 1H, 13C and 15N resonance assignments of the Bright/ARID domain from the human JARID1C (SMCX) protein.
Biomol.Nmr Assign., 2, 2008
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2Q9G
 | | Crystal structure of human cytochrome P450 46A1 | | 分子名称: | Cytochrome P450 46A1, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | White, M.A, Mast, N.V, Johnson, E.F, Stout, C.D, Pikuleva, I.A. | | 登録日 | 2007-06-12 | | 公開日 | 2008-06-17 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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2FTP
 | | Crystal Structure of hydroxymethylglutaryl-CoA lyase from Pseudomonas aeruginosa | | 分子名称: | GLYCEROL, SODIUM ION, hydroxymethylglutaryl-CoA lyase | | 著者 | Xiao, T, Evdokimova, E, Liu, Y, Kudritska, M, Savchenko, A, Pai, E.F, Edwards, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2006-01-24 | | 公開日 | 2006-03-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structure of hydroxymethylglutaryl-CoA lyase from Pseudomonas aeruginosa
To be Published
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2JBY
 | | A viral protein unexpectedly mimics the structure and function of pro- survival Bcl-2 | | 分子名称: | BCL-2 HOMOLOGOUS ANTAGONIST/KILLER 2, M11L PROTEIN, SODIUM ION | | 著者 | Kvansakul, M, Van Delft, M.F, Lee, E.F, Gulbis, J.M, Fairlie, W.D, Huang, D.C.S, Colman, P.M. | | 登録日 | 2006-12-14 | | 公開日 | 2007-03-27 | | 最終更新日 | 2018-06-13 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | A structural viral mimic of prosurvival Bcl-2: a pivotal role for sequestering proapoptotic Bax and Bak.
Mol. Cell, 25, 2007
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2FDV
 | | Microsomal P450 2A6 with the inhibitor N-Methyl(5-(pyridin-3-yl)furan-2-yl)methanamine bound | | 分子名称: | 1,2-ETHANEDIOL, Cytochrome P450 2A6, N-METHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE, ... | | 著者 | Yano, J.K, Stout, C.D, Johnson, E.F. | | 登録日 | 2005-12-14 | | 公開日 | 2006-11-28 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Synthetic Inhibitors of Cytochrome P-450 2A6: Inhibitory Activity, Difference Spectra, Mechanism of Inhibition, and Protein Cocrystallization.
J.Med.Chem., 49, 2006
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2JBX
 | | Crystal Structure of the myxoma virus anti-apoptotic protein M11L | | 分子名称: | M11L PROTEIN | | 著者 | Kvansakul, M, Van Delft, M.F, Lee, E.F, Gulbis, J.M, Fairlie, W.D, Huang, D.C.S, Colman, P.M. | | 登録日 | 2006-12-14 | | 公開日 | 2007-03-27 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | | 主引用文献 | A Structural Viral Mimic of Prosurvival Bcl-2: A Pivotal Role for Sequestering Proapoptotic Bax and Bak.
Mol.Cell, 25, 2007
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2FDY
 | | Microsomal P450 2A6 with the inhibitor Adrithiol bound | | 分子名称: | 4,4'-DIPYRIDYL DISULFIDE, Cytochrome P450 2A6, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Yano, J.K, Stout, C.D, Johnson, E.F. | | 登録日 | 2005-12-14 | | 公開日 | 2006-11-28 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Synthetic Inhibitors of Cytochrome P-450 2A6: Inhibitory Activity, Difference Spectra, Mechanism of Inhibition, and Protein Cocrystallization.
J.Med.Chem., 49, 2006
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4EHQ
 | | Crystal Structure of Calmodulin Binding Domain of Orai1 in Complex with Ca2+/Calmodulin Displays a Unique Binding Mode | | 分子名称: | CALCIUM ION, Calcium release-activated calcium channel protein 1, Calmodulin, ... | | 著者 | Liu, Y, Zheng, X, Mueller, G.A, Sobhany, M, DeRose, E.F, Zhang, Y, London, R.E, Birnbaumer, L. | | 登録日 | 2012-04-03 | | 公開日 | 2012-11-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.9005 Å) | | 主引用文献 | Crystal structure of calmodulin binding domain of orai1 in complex with ca2+*calmodulin displays a unique binding mode.
J.Biol.Chem., 287, 2012
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2MWN
 | | Talin-F3 / RIAM N-terminal Peptide complex | | 分子名称: | Amyloid beta A4 precursor protein-binding family B member 1-interacting protein, Talin-1 | | 著者 | Yang, J, Zhu, L, Zhang, H, Hirbawi, J, Fukuda, K, Dwivedi, P, Liu, J, Byzova, T, Plow, E.F, Wu, J, Qin, J. | | 登録日 | 2014-11-13 | | 公開日 | 2014-12-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Conformational activation of talin by RIAM triggers integrin-mediated cell adhesion.
Nat Commun, 5, 2014
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2NNI
 | | CYP2C8dH complexed with montelukast | | 分子名称: | Cytochrome P450 2C8, MONTELUKAST, PALMITIC ACID, ... | | 著者 | Schoch, G.A, Yano, J.K, Stout, C.D, Johnson, E.F. | | 登録日 | 2006-10-24 | | 公開日 | 2007-10-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Determinants of cytochrome P450 2C8 substrate binding: structures of complexes with montelukast, troglitazone, felodipine, and 9-cis-retinoic acid.
J.Biol.Chem., 283, 2008
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