2JBY
A viral protein unexpectedly mimics the structure and function of pro- survival Bcl-2
Summary for 2JBY
Entry DOI | 10.2210/pdb2jby/pdb |
Related | 2JBX |
Descriptor | M11L PROTEIN, BCL-2 HOMOLOGOUS ANTAGONIST/KILLER 2, SODIUM ION, ... (4 entities in total) |
Functional Keywords | apoptosis |
Biological source | MYXOMA VIRUS More |
Total number of polymer chains | 2 |
Total formula weight | 19505.10 |
Authors | Kvansakul, M.,Van Delft, M.F.,Lee, E.F.,Gulbis, J.M.,Fairlie, W.D.,Huang, D.C.S.,Colman, P.M. (deposition date: 2006-12-14, release date: 2007-03-27, Last modification date: 2018-06-13) |
Primary citation | Kvansakul, M.,van Delft, M.F.,Lee, E.F.,Gulbis, J.M.,Fairlie, W.D.,Huang, D.C.,Colman, P.M. A structural viral mimic of prosurvival Bcl-2: a pivotal role for sequestering proapoptotic Bax and Bak. Mol. Cell, 25:933-942, 2007 Cited by PubMed: 17386268DOI: 10.1016/j.molcel.2007.02.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.41 Å) |
Structure validation
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