2JBY
A viral protein unexpectedly mimics the structure and function of pro- survival Bcl-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | M11L PROTEIN | polymer | 145 | 16600.0 | 1 | UniProt (Q85295) Pfam (PF11099) | MYXOMA VIRUS | APOPTOSIS REGULATOR M11L, M11L |
| 2 | B (B) | BCL-2 HOMOLOGOUS ANTAGONIST/KILLER 2 | polymer | 26 | 2882.2 | 1 | UniProt (Q13014) UniProt (by SIFTS) (Q16611) | HOMO SAPIENS | APOPTOSIS REGULATOR BAK-2, BAK |
| 3 | C (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 58 | Chemie (HOH) |
Sequence modifications
A: 1 - 132 (UniProt: Q85295)
| PDB | External Database | Details |
|---|---|---|
| Met -12 | - | expression tag |
| Gly -11 | - | expression tag |
| Ser -10 | - | expression tag |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Met 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 19482.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 23.0 | |
| All* | Total formula weight | 19505.1 |
