4ONJ
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3UIJ
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![BU of 3uij by Molmil](/molmil-images/mine/3uij) | |
3UIH
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3UIG
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3UII
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4FSX
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6DRJ
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![BU of 6drj by Molmil](/molmil-images/mine/6drj) | Structure of TRPM2 ion channel receptor by single particle electron cryo-microscopy, ADPR/Ca2+ bound state | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, CALCIUM ION, Transient receptor potential cation channel, ... | 著者 | Du, J, Lu, W, Huang, Y, Winkler, P, Sun, W. | 登録日 | 2018-06-12 | 公開日 | 2018-09-19 | 最終更新日 | 2018-10-10 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium. Nature, 562, 2018
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6DRK
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![BU of 6drk by Molmil](/molmil-images/mine/6drk) | Structure of TRPM2 ion channel receptor by single particle electron cryo-microscopy, Apo state | 分子名称: | Transient receptor potential cation channel, subfamily M, member 2 | 著者 | Du, J, Lu, W, Huang, Y, Winkler, P, Sun, W. | 登録日 | 2018-06-12 | 公開日 | 2018-09-19 | 最終更新日 | 2018-10-10 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium. Nature, 562, 2018
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3BKY
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![BU of 3bky by Molmil](/molmil-images/mine/3bky) | Crystal Structure of Chimeric Antibody C2H7 Fab in complex with a CD20 Peptide | 分子名称: | B-lymphocyte antigen CD20, the Fab fragment of chimeric 2H7, heavy chain, ... | 著者 | Du, J, Zhong, C, Ding, J. | 登録日 | 2007-12-07 | 公開日 | 2008-04-29 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Crystal structure of chimeric antibody C2H7 Fab in complex with a CD20 peptide Mol.Immunol., 45, 2008
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3IU3
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![BU of 3iu3 by Molmil](/molmil-images/mine/3iu3) | Crystal structure of the Fab fragment of therapeutic antibody Basiliximab in complex with IL-2Ra (CD25) ectodomain | 分子名称: | Heavy chain of Fab fragment of Basiliximab, Interleukin-2 receptor alpha chain, Light chain of Fab fragment of Basiliximab, ... | 著者 | Du, J, Yang, H, Wang, J, Ding, J. | 登録日 | 2009-08-29 | 公開日 | 2010-01-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis for the blockage of IL-2 signaling by therapeutic antibody basiliximab J.Immunol., 184, 2010
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8D8R
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![BU of 8d8r by Molmil](/molmil-images/mine/8d8r) | SARS-CoV-2 Spike RBD in complex with DMAb 2196 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2196 heavy chain, 2196 light chain, ... | 著者 | Du, J, Cui, J, Pallesen, J. | 登録日 | 2022-06-08 | 公開日 | 2022-10-19 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2. Nat Commun, 13, 2022
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8D8Q
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![BU of 8d8q by Molmil](/molmil-images/mine/8d8q) | SARS-CoV-2 Spike RBD in complex with DMAbs 2130 and 2196 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2130 heavy chain, 2130 light chain, ... | 著者 | Du, J, Cui, J, Pallesen, J. | 登録日 | 2022-06-08 | 公開日 | 2022-10-19 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2. Nat Commun, 13, 2022
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4ONQ
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4QEN
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![BU of 4qen by Molmil](/molmil-images/mine/4qen) | crystal structure of KRYPTONITE in complex with mCHH DNA and SAH | 分子名称: | DNA (5'-D(*AP*CP*TP*GP*AP*TP*GP*AP*GP*TP*AP*CP*CP*AP*T)-3'), DNA (5'-D(*GP*GP*TP*AP*CP*TP*(5CM)P*AP*TP*CP*AP*GP*TP*AP*T)-3'), Histone-lysine N-methyltransferase, ... | 著者 | Du, J, Li, S, Patel, D.J. | 登録日 | 2014-05-17 | 公開日 | 2014-07-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | 主引用文献 | Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE. Mol.Cell, 55, 2014
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4QEO
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![BU of 4qeo by Molmil](/molmil-images/mine/4qeo) | crystal structure of KRYPTONITE in complex with mCHH DNA, H3(1-15) peptide and SAH | 分子名称: | DNA 5'-ACTGATGAGTACCAT-3', DNA 5'-GGTACT(5CM)ATCAGTAT-3', Histone H3, ... | 著者 | Du, J, Li, S, Patel, D.J. | 登録日 | 2014-05-17 | 公開日 | 2014-07-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE. Mol.Cell, 55, 2014
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4QEP
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![BU of 4qep by Molmil](/molmil-images/mine/4qep) | crystal structure of KRYPTONITE in complex with mCHG DNA and SAH | 分子名称: | DNA (5'-D(*AP*CP*TP*GP*CP*TP*GP*AP*GP*TP*AP*CP*CP*AP*T)-3'), DNA (5'-D(*GP*GP*TP*AP*CP*TP*(5CM)P*AP*GP*CP*AP*GP*TP*AP*T)-3'), Histone-lysine N-methyltransferase, ... | 著者 | Du, J, Li, S, Patel, D.J. | 登録日 | 2014-05-17 | 公開日 | 2014-07-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE. Mol.Cell, 55, 2014
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3CXD
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![BU of 3cxd by Molmil](/molmil-images/mine/3cxd) | Crystal structure of anti-osteopontin antibody 23C3 in complex with its epitope peptide | 分子名称: | Fab fragment of anti-osteopontin antibody 23C3, Heavy chain, Light chain, ... | 著者 | Du, J, Yang, H, Zhong, C, Ding, J. | 登録日 | 2008-04-24 | 公開日 | 2008-10-14 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis J.Mol.Biol., 382, 2008
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7N29
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![BU of 7n29 by Molmil](/molmil-images/mine/7n29) | Structure of NAD kinase | 分子名称: | NAD kinase 2, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Du, J, Estrella, M.A, Jeffrey, P.D, Korennykh, A.V. | 登録日 | 2021-05-28 | 公開日 | 2022-05-04 | 最終更新日 | 2022-06-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of human NADK2 reveals atypical assembly and regulation of NAD kinases from animal mitochondria. Proc.Natl.Acad.Sci.USA, 119, 2022
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3DSF
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![BU of 3dsf by Molmil](/molmil-images/mine/3dsf) | Crystal structure of anti-osteopontin antibody 23C3 in complex with W43A mutated epitope peptide | 分子名称: | Fab fragment of anti-osteopontin antibody 23C3, Heavy chain, Light chain, ... | 著者 | Du, J, Zhong, C, Yang, H, Ding, J. | 登録日 | 2008-07-12 | 公開日 | 2008-10-14 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis J.Mol.Biol., 382, 2008
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4NJ5
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![BU of 4nj5 by Molmil](/molmil-images/mine/4nj5) | Crystal structure of SUVH9 | 分子名称: | Probable histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH9, ZINC ION | 著者 | Du, J, Patel, D.J. | 登録日 | 2013-11-08 | 公開日 | 2014-01-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | SRA- and SET-domain-containing proteins link RNA polymerase V occupancy to DNA methylation. Nature, 507, 2014
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2OSL
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![BU of 2osl by Molmil](/molmil-images/mine/2osl) | Crystal structure of Rituximab Fab in complex with an epitope peptide | 分子名称: | B-lymphocyte antigen CD20, heavy chain of the Rituximab Fab fragment,heavy chain of the Rituximab Fab fragment, light chain of the Rituximab Fab fragment,light chain of the Rituximab Fab fragment | 著者 | Du, J, Zhong, C, Ding, J. | 登録日 | 2007-02-06 | 公開日 | 2007-04-10 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for recognition of CD20 by therapeutic antibody Rituximab J.Biol.Chem., 282, 2007
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3WFV
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![BU of 3wfv by Molmil](/molmil-images/mine/3wfv) | HIV-1 CRF07 gp41 | 分子名称: | Envelope glycoprotein gp160 | 著者 | Du, J, Xue, H, Ma, J, Liu, F, Zhou, J, Shao, Y, Qiao, W, Liu, X. | 登録日 | 2013-07-24 | 公開日 | 2013-10-16 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The crystal structure of HIV CRF07 B'/C gp41 reveals a hyper-mutant site in the middle of HR2 heptad repeat Virology, 446, 2013
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3GIZ
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![BU of 3giz by Molmil](/molmil-images/mine/3giz) | Crystal structure of the Fab fragment of anti-CD20 antibody Ofatumumab | 分子名称: | Fab fragment of anti-CD20 antibody Ofatumumab, heavy chain, light chain, ... | 著者 | Du, J, Yang, H, Ding, J. | 登録日 | 2009-03-07 | 公開日 | 2009-05-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the Fab fragment of therapeutic antibody Ofatumumab provides insights into the recognition mechanism with CD20 Mol.Immunol., 46, 2009
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4FT4
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4FT2
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